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MLL/MLLT1 Fusion Gene

Known as: MLL/ENL Fusion Gene, ENL/MLL FUSION GENE, KMT2A/MLLT1 Fusion Gene 
A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.3) which fuses the 5' half of the MLL gene to most of the MLLT1 gene… Expand
National Institutes of Health

Papers overview

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2014
2014
C/EBPα collaborates with MLL-ENL to activate a group of genes that, together with Hoxa9 and Meis1, are responsible for the early… Expand
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Highly Cited
2012
Highly Cited
2012
The elongation stage of transcription is highly regulated in metazoans. We previously purified the AFF1- and AFF4-containing… Expand
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Review
2008
Review
2008
Erythema nodosum leprosum (ENL) is an immune-mediated complication of leprosy presenting with inflammatory skin nodules and… Expand
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Highly Cited
2007
Highly Cited
2007
The aim of this study was to identify immunobiological subgroups in 133 infant acute lymphoblastic leukemia (ALL) cases as… Expand
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Highly Cited
2006
Highly Cited
2006
Abdominal-type HoxA genes in combination with Meis1 are well-documented on-cogenes in various leukemias but it is unclear how… Expand
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Highly Cited
2005
Highly Cited
2005
The t[(11;19)(p22;q23)] translocation, which gives rise to the MLL-ENL fusion protein, is commonly found in infant acute… Expand
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1999
1999
Translocations affecting the chromosomal locus 11q23 are hallmarks of infant leukemias. These events disrupt the MLL gene (also… Expand
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Review
1998
Review
1998
A large number of continuous human leukemia cell lines have been established over the last three decades. Clearly, leukemia cell… Expand
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Highly Cited
1998
Highly Cited
1998
The HRX gene (also called MLL, ALL-1, and Htrx) at chromosome band 11q23 is associated with specific subsets of acute leukemias… Expand
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Highly Cited
1997
Highly Cited
1997
A subset of chromosomal translocations in acute leukemias results in the fusion of the trithorax-related protein HRX with a… Expand
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