MLL/MLLT1 Fusion Gene

Known as: ENL/MLL FUSION GENE, KMT2A/MLLT1 Fusion Gene, KMT2A-MLLT1 Fusion Gene 
A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.3) which fuses the 5' half of the MLL gene to most of the MLLT1 gene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
01219972017

Papers overview

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2017
2017
Citation: Wille JJ. Role of Epigenetic Regulation of Growth Arrest States in Normal and Cancer Cells. J Clin Epigenet. 2017, 3:1… (More)
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2017
2017
Translocations involving the mixed lineage leukemia-1 are recurrent events in acute leukemia and associate with lymphoid (ALL… (More)
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2014
2014
MLL-fusion proteins are potent inducers of oncogenic transformation, and their expression is considered to be the main oncogenic… (More)
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2013
2013
Acute leukaemia is the most common form of childhood cancer and is the primary cause of cancer-related mortality in children. The… (More)
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2013
2013
MLL rearrangements are a genetic hallmark of acute leukemia patients, which exhibit a particular poor outcome. To date, more than… (More)
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2005
2005
The t[(11;19)(p22;q23)] translocation, which gives rise to the MLL-ENL fusion protein, is commonly found in infant acute… (More)
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Review
2001
Review
2001
PURPOSE To compare the success rates of external dacryocystorhinostomy (EXT-DCR) with 5-fluorouracil (5-FU) augmented endonasal… (More)
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1999
1999
Translocations affecting the chromosomal locus 11q23 are hallmarks of infant leukemias. These events disrupt the MLL gene (also… (More)
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Highly Cited
1998
Highly Cited
1998
The HRX gene (also called MLL, ALL-1, and Htrx) at chromosome band 11q23 is associated with specific subsets of acute leukemias… (More)
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Highly Cited
1997
Highly Cited
1997
A subset of chromosomal translocations in acute leukemias results in the fusion of the trithorax-related protein HRX with a… (More)
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