MK 912

Known as: MK-912 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
02419892017

Papers overview

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2004
2004
This study analyzed the regulation of alpha2-adrenoceptors (alpha2-ARs) in human vascular smooth muscle cells (VSMs). Saphenous… (More)
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2002
2002
1. Type 4 phosphodiesterase (PDE4) inhibitors mimic the pharmacological actions of alpha(2)-adrenoceptor antagonists. This has… (More)
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2001
2001
How and why the chemical stability of amorphous solid is different from crystalline solid is an important problem. In this study… (More)
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2001
2001
The objective of this work was to assess the role of alpha(2)-adrenoceptors in emesis induced by inhibitors of type 4… (More)
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Highly Cited
2000
Highly Cited
2000
Cold constricts cutaneous blood vessels by increasing the reactivity of smooth muscle alpha(2)-adrenergic receptors (alpha(2)-ARs… (More)
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1998
1998
In vitro studies showed that MK-912 ((2S, 12bS)1',3'-dimethylspiro(1,3,4,5',6,6',7,12b-octahydro -2H-benzo[b]furo[2,3-a… (More)
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1998
1998
1. The mechanism underlying the anticataleptic properties of the atypical neuroleptic agent, clozapine, has been investigated in… (More)
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1991
1991
We used MK-912, a potent new selective alpha 2-adrenergic receptor antagonist that is active orally, to study the effect of short… (More)
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1989
1989
L-657,743 (MK-912), a highly potent and selective alpha 2-adrenoceptor antagonist was tritiated to a high specific activity and… (More)
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1989
1989
MK-912, a new alpha 2-adrenoceptor antagonist, was assessed in six volunteers by use of antagonism of the effects of intravenous… (More)
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