MK-8141

Known as: ACT-077825 
 

Topic mentions per year

Topic mentions per year

2010-2014
0120102014

Papers overview

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2014
2014
BACKGROUND/AIMS The study objective was to investigate and compare the pharmacokinetics of a single oral dose of ACT-077825, a… (More)
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2013
2013
This study was conducted to characterize the multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-077825, a… (More)
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2013
2013
This open-label, randomized study evaluated the effects of steady-state diltiazem on the pharmacokinetic, safety, and… (More)
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2012
2012
To evaluate the pharmacokinetics, pharmacodynamics, safety, and tolerability of escalating single oral doses of ACT-077825, a… (More)
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2010
2010
The renin inhibitor MK-8141 (ACT-077825) demonstrates substantial immunoreactive active renin (ir-AR) increase (sevenfold… (More)
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