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MK 447

Known as: MK-447 
National Institutes of Health

Papers overview

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Highly Cited
1993
Highly Cited
1993
Whole cell Cl- currents in human neutrophils induced by cell swelling.
The properties of the conductive Cl- transport pathway underlying regulatory volume decrease (RVD) in human neutrophils were… 
1991
1991
Evidence for the O-sulfo derivative of MK-447 as active metabolite of MK-447.
1988
1988
An investigation of the novel anti-inflammatory agents ONO-3144 and MK-447. Studies on their potential antioxidant activity.
1985
1985
Lipid peroxidation modifies the effect of phenolic anti-inflammatory drugs on prostaglandin biosynthesis.
1985
1985
Identification of hydrogen peroxide and hydroxyl radicals as mediators of leukocyte-induced myocardial dysfunction. Limitation of infarct size with neutrophil inhibition and depletion.
Neutrophil infiltration of the myocardium is an important component of such diverse disease entities as myocarditis, ischemia… 
1984
1984
Enhanced prostacyclin generation by phenolic compounds acting as a tryptophan-like cofactor of PG hydroperoxidase.
1983
1983
Failure of various agents to decrease oleic acid pulmonary albumin leak.
1981
1981
Beneficial actions of a free radical scavenger in traumatic shock and myocardial ischemia.
The role of prostanoids in shock states is complex because beneficial as well as deleterious prostanoids are formed during… 
1980
1980
Dual effects of a basic anti-inflammatory agent, 2-aminomethyl-4-t-butyl-6-iodophenol hydrochloride (MK-447), on biosynthesis of prostaglandin endoperoxides.
Effects of MK-447 on prostaglandin (PG) endoperoxide formation from arachidonic acid by bovine seminal vesicle microsomes in the… 
1979
1979
Effects of 2-aminomethyl-4-t-butyl-6-iodophenol (MK-447) on granulomatous inflammation: Lack of correlation with changes in levels of prostaglandin-like material
MK-447, administered locally to carrageenan-soaked sponges implanted in the backs of rats, either on the day of implantation (day… 
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