MK 0518

Known as: 0518, MK, MK-0518, MK0518 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Human HIV integrase inhibitors are a novel class of antiretroviral drugs that act by blocking incorporation of the proviral DNA… (More)
  • table 1
  • table 1
  • table 2
  • table 3
  • figure 1
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Integration of viral DNA into the host chromosome is an essential step in the life cycle of retroviruses and is facilitated by… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Raltegravir (MK-0518) is a potent inhibitor of human immunodeficiency virus (HIV) integrase and is clinically effective against… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Raltegravir (MK-0518) is the first integrase (IN) inhibitor to be approved by the US FDA and is currently used in clinical… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
BACKGROUND Raltegravir (MK-0518) is an HIV-1 integrase inhibitor with potent in-vitro activity against HIV-1 strains including… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Raltegravir is a potent human immunodeficiency virus 1 (HIV-1) integrase strand transfer inhibitor that is being developed as a… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
OBJECTIVE Raltegravir (MK-0518) belongs to the new class of HIV integrase inhibitors. To date, there have been no reports… (More)
Is this relevant?
2007
2007
An HPLC-MS/MS method was developed for the determination of MK-0518 (raltegravir), an HIV integrase inhibitor, in human plasma… (More)
Is this relevant?
Review
2007
Review
2007
In the developed world, access to highly active antiretroviral therapy (HAART) has led to significant reductions in the morbidity… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
BACKGROUND MK-0518 is a novel HIV-1 integrase strand transfer inhibitor with potent in vitro activity against HIV-1 (95… (More)
Is this relevant?