MIXED LINEAGE LEUKEMIA

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
010203019962018

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2013
2013
MicroRNAs (miRNAs), small noncoding RNAs that regulate target gene mRNAs, are known to contribute to pathogenesis of cancers… (More)
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Highly Cited
2011
Highly Cited
2011
Mislocated enzymatic activity of DOT1L has been proposed as a driver of leukemogenesis in mixed lineage leukemia (MLL). The… (More)
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Highly Cited
2011
Highly Cited
2011
The histone 3 lysine 79 (H3K79) methyltransferase Dot1l has been implicated in the development of leukemias bearing… (More)
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2010
2010
Chromosomal translocations targeting the mixed lineage leukemia (MLL) gene result in MLL fusion proteins that are found in… (More)
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Highly Cited
2010
Highly Cited
2010
MicroRNA (miRNA)-17-92 cluster (miR-17-92), containing seven individual miRNAs, is frequently amplified and overexpressed in… (More)
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2008
Highly Cited
2008
WDR5 is a component of the mixed lineage leukemia (MLL) complex, which methylates lysine 4 of histone H3, and was identified as a… (More)
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2004
Highly Cited
2004
Activating mutations of the FLT3 receptor tyrosine kinase are common in acute myelogenous leukemia (AML) but are rare in adult… (More)
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Highly Cited
2003
Highly Cited
2003
Chromosomal abnormalities involving the Mixed Lineage Leukemia (MLL) gene at 11q23 are among the most frequent cytogenetic… (More)
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Highly Cited
2003
Highly Cited
2003
Infant acute lymphoblastic leukemia (ALL) is characterized by a high incidence of mixed lineage leukemia (MLL) gene… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE To evaluate the incidence and clinical significance of partial tandem duplications (PTDs) of the mixed lineage leukemia… (More)
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