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Bcl2-associated athanogene (BAG)2 as a co-chaperone has been demonstrated to be involved in tumor growth and metastasis, but its… Expand 目的探讨miRNA-186-5p在乳腺癌细胞阿霉素耐药性逆转作用中的分子机制。 方法采用阿霉素诱导人乳腺癌细胞系MCF-7，建立阿霉素耐药性细胞株，命名为MCF-7/ADR；采用双荧光素酶实验检测miR-186-5p与RAB2A的靶向结合情况；采用qRT… Expand Increasing evidences suggest that inflammatory microenvironment has a crucial role in prostate cancer (PCa) progression; however… Expand Prostate cancer (PCa) is the second leading cause of cancer-related deaths in north American men, and most its related deaths are… Expand ABSTRACT Introduction: Endometrial cancer is the most frequent gynecological malignancy in the developed world. Currently… Expand Glioblastoma remains one of the most lethal types of cancer, and is the most common brain tumor in adults. The purpose of this… Expand The conversion of melanocytes into cutaneous melanoma is largely dictated by the effects of solar ultraviolet radiation (UVR… Expand Deeper mechanistic understanding of lung adenocarcinoma (non-small cell lung carcinoma, or NSCLC), a leading cause of cancer… Expand OBJECTIVE
To explore the expression of hsa-mir-186 in colorectal cancer and study its role in regulating the biological behaviors… Expand Deeper mechanistic understanding of lung adenocarcinoma (non–small cell lung carcinoma, or NSCLC), a leading cause of cancer… Expand