METHIONINE ADENOSYLTRANSFERASE

Known as: S-Adenosylmethionine Synthetase, ATP:L-methionine S-adenosyltransferase, Methionine Adenosyltransferase [Chemical/Ingredient] 
An enzyme that catalyzes the synthesis of S-adenosylmethionine from methionine and ATP. EC 2.5.1.6.
National Institutes of Health

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Broader (1)

Alkyltransferases
In BloodMAT1A geneProcess of secretionantagonists & inhibitors
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Papers overview

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Highly Cited
2013
Highly Cited
2013
MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma.
MicroRNAs (miRNAs) and methionine adenosyltransferase 1A (MAT1A) are dysregulated in hepatocellular carcinoma (HCC), and reduced… (More)
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Highly Cited
2011
Highly Cited
2011
Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein.
Protein methylation pathways comprise methionine adenosyltransferase (MAT), which produces S-adenosylmethionine (SAM) and SAM… (More)
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Review
2007
Review
2007
Role of S-adenosyl-L-methionine in liver health and injury.
S-adenosylmethionine (SAMe) has rapidly moved from being a methyl donor to a key metabolite that regulates hepatocyte growth… (More)
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Highly Cited
2006
Highly Cited
2006
Differential inhibition of Arabidopsis methionine adenosyltransferases by protein S-nitrosylation.
In animals, protein S-nitrosylation, the covalent attachment of NO to the thiol group of cysteine residues, is an intensively… (More)
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Review
2005
Review
2005
Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.
Two genes (MAT1A and MAT2A) encode for the essential enzyme methionine adenosyltransferase (MAT), which catalyzes the… (More)
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Highly Cited
2002
Highly Cited
2002
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.
In mammals, methionine metabolism occurs mainly in the liver via methionine adenosyltransferase-catalyzed conversion to S… (More)
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Highly Cited
2000
Highly Cited
2000
Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver.
Liver-specific and non-liver-specific methionine adenosyltransferase (MAT) are products of two genes, MAT1A and MAT2A… (More)
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Highly Cited
1998
Highly Cited
1998
Changes in methionine adenosyltransferase during liver regeneration in the rat.
Liver-specific and non-liver-specific methionine adenosyltransferase (MAT) are products of two genes (MAT1A and MAT2A… (More)
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Review
1993
Review
1993
Methionine adenosyltransferase: structure and function.
Methionine adenosyltransferase (MAT), a key enzyme in metabolism, catalyzes the synthesis of one of the most important and… (More)
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Highly Cited
1986
Highly Cited
1986
Methionine metabolism in mammals. Adaptation to methionine excess.
We conducted a systematic evaluation of the effects of increasing levels of dietary methionine on the metabolites and enzymes of… (More)
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