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MENTAL RETARDATION, X-LINKED 34 (disorder)

Known as: MENTAL RETARDATION, X-LINKED 34, MRX34 
 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
As FDA-approved small RNA drugs start to enter clinical medicine, ongoing studies for the microRNA (miRNA) class of small RNAs… Expand
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Highly Cited
2016
Highly Cited
2016
SummaryPurpose Naturally occurring tumor suppressor microRNA-34a (miR-34a) downregulates the expression of >30 oncogenes across… Expand
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Highly Cited
2016
Highly Cited
2016
Background: Although clinical studies have shown promise for targeting PD1/PDL1 signaling in non–small cell lung cancer (NSCLC… Expand
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2016
2016
Background: Despite recent progress in multiple myeloma (MM) treatment with the advent of new targeted anticancer agents such as… Expand
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2016
2016
Background: miRNAs play a critical role in regulating key biological processes by modulating the expression of up to several… Expand
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2015
2015
Background: MRX34 is a liposomal nanoparticle formulation with an encapsulated mimic of the naturally occurring microRNA-34 (miR… Expand
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2015
2015
MRX34 has recently entered the clinic as the first therapeutic product based on a microRNA (miRNA) mimic. In order to measure… Expand
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2015
2015
Background Although clinical studies have shown promise for targeting PD1/PDL1 signaling in non-small cell lung cancer (NSCLC… Expand
Is this relevant?
2014
2014
MRX34, a microRNA (miRNA)-based therapy for cancer, has recently entered clinical trials as the first clinical candidate in its… Expand
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2014
2014
Background: MRX34 is a liposome-formulated double-stranded mimic of tumor suppressor microRNA-34 (miR-34), which is lost or… Expand
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