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MELK Inhibitor OTS167
Known as:
OTS167
An orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167…
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National Institutes of Health
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Papers overview
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2018
2018
Mouse Serum : Application to a Pharmacokinetic Study
W. Yong
,
Vinod Vijay Subhash
,
+12 authors
Lingzhi Wang
2018
Corpus ID: 52094016
Validation of a LC-MS/MS Method for Quantitative Analysis of MELK Inhibitor OTS167 in Mouse Serum: Application to a…
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2017
2017
Clinical significance of maternal embryonic leucine-zipper kinase (MELK) expression and evaluation of OTS167 (MELK inhibitor) in ovarian cancer
Ikeda Yuji
,
Sato Sho
,
+6 authors
Hasegawa Kosei
2017
Corpus ID: 89740992
2015
2015
Glucuronidation of OTS 167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT 1 A 1 , UGT 1 A 3 , UGT 1 A 8 , and UGT 1 A 10 s
J. Ramírez
,
S. Mirkov
,
M. Ratain
2015
Corpus ID: 5562805
OTS167 is a potent maternal embryonic leucine zipper kinase inhibitor undergoing clinical testing as antineoplastic agent. We…
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