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MEDI4893

 
National Institutes of Health

Papers overview

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2019
2019
Abstract Background Suvratoxumab (suvra), an extended half-life (~80 days), Staphylococcus aureus (SA) alpha toxin-neutralizing… Expand
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2018
2018
Abstract Objectives MEDI4893 is a novel, long‐acting human monoclonal antibody targeting Staphylococcus aureus (SA) alpha toxin… Expand
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2018
2018
Alpha toxin (AT) is a cytolytic pore-forming toxin that plays a key role in Staphylococcus aureus pathogenesis; consequently… Expand
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2017
2017
ABSTRACT The role broad-spectrum antibiotics play in the spread of antimicrobial resistance, coupled with their effect on the… Expand
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2016
2016
ABSTRACT MEDI4893 is an investigational immunoglobulin G1(κ) monoclonal antibody that specifically binds to and neutralizes alpha… Expand
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2016
2016
ABSTRACT Staphylococcus aureus infections lead to an array of illnesses ranging from mild skin infections to serious diseases… Expand
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2015
2015
ABSTRACT Immunocompromised individuals are at increased risk of Staphylococcus aureus pneumonia. Neutralization of alpha-toxin… Expand
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2014
2014
Background: MEDI4893 is an anti-α-toxin (AT) antibody currently in clinical trial in the field of Staphylococcus aureus-mediated… Expand
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2014
2014
ABSTRACT Alpha-toxin (AT) is a major virulence determinant in Staphylococcus aureus skin and soft tissue infection models. We… Expand
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2014
2014
MEDI4893 is a neutralizing human monoclonal antibody that targets alpha toxin (AT), and is currently undergoing evaluation in the… Expand
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