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MEDI4736

Known as: Immunoglobulin G1, Anti-(Human Protein B7-H1) (Human Monoclonal MEDI4736 Heavy Chain), Disulfide with Human Monoclonal MEDI4736 Kappa-chain, Dimer, MEDI-4736 
National Institutes of Health

Papers overview

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2017
2017
162Background: Recent data suggests 25-30% of sporadic mCRPC has defects in DNA repair pathways which may confer sensitivity to… 
2017
2017
572Background: Pathologic complete response (pCR) rates to neoadjuvant chemotherapy in TNBC plateaued at 40% with existing… 
2016
2016
9029Background: The PD-1/PD-L1 axis is an important immune inhibitory pathway contributing to tumor cell escape from… 
2015
2015
Meeting abstracts As single agents, durvalumab (MEDI4736), a human IgG1 anti-PD-L1 antibody, and tremelimumab, a human IgG2 anti… 
2014
2014
2602 Background: MEDI4736 is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody directed against human programmed death… 
2014
2014
TPS3120^ Background: MEDI4736 (M) is a human IgG1 monoclonal antibody that binds specifically to programmed cell death ligand 1… 
Review
2014
Review
2014
A review and critical consideration of immunotherapeutical concepts in non-small cell lung cancer (NSCLC) is given. Nivolumab… 
Review
2007
Review
2007
B7-H1encompasses a recently discovered cell surface glycoprotein within the B7 family of T-cell coregulatory molecules. B7…