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MDM2 gene
Known as:
ONCOPROTEIN MDM2
, HDM2
, MDM2
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This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis.
National Institutes of Health
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Related topics
Related topics
15 relations
Atypical Lipoma
Cell Cycle Control
Inflammatory Liposarcoma
Liposarcoma, well differentiated
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
MDM2 Gen Polymorphisms at Acute Myeloid Leukemia Patients
C. Tekin
,
S. Oğuzkan
,
+5 authors
M. Pehlivan
2016
Corpus ID: 78592557
Purpose: Leukemia is a malignant disease which is caused by bone marrow lymphopoietic or hematopoietic stem cells. Acute myeloid…
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2016
2016
THE CRISPR/CAS9-CREATED MDM2 T309G ENHANCES VITREOUS-INDUCED EXPRESSION OF MDM2 AND PROLIFERATION AND SURVIVAL OF CELLS
Y. Duan
,
Gaoen Ma
,
Xionggao Huang
,
P. D'Amore
,
Feng Zhang
,
H. Lei
2016
Corpus ID: 106406183
The 309G allele of single nucleotide polymorphisms (SNPs) in the mouse double minute ( MDM2) promoter locus is associated with a…
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2013
2013
P 53 Arg 72 Pro and MDM 2 SNP 309 Polymorphisms Cooperate to Increase Lung Adenocarcinoma Risk in Chinese Female Non-smokers : A Case Control Study
Yangwu Ren
,
Zhi-Hua Yin
,
+4 authors
Baosen Zhou
2013
Corpus ID: 20246454
Lung cancer is one of the leading causes of cancerrelated deaths in the world (Jemal et al.,2011). Cigarette smoking is…
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2011
2011
The interaction of p53 and MDM2 genes in cancers, in silico studies and phylogenetic analysis
A. Jayaraman
,
K. Jamil
,
S. Raju
2011
Corpus ID: 86141151
The normal cell cycle process is a crucial process and is generally mediated by a number of regulatory genes. One of the most…
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2010
2010
Association between MDM2 SNP309 Polymorphism and Breast Cancer Risk in Chinese Women
Can Wu
,
Ye Xu
,
+6 authors
Yun-tao Xie
2010
Corpus ID: 79896688
2008
2008
SNP309 as predictor for sensitivity of CLL cells to the MDM2 inhibitor nutlin-3a.
Irina Seyfried
,
S. Hofbauer
,
M. Stoecher
,
R. Greil
,
I. Tinhofer
Blood
2008
Corpus ID: 206871333
To the editor: From a recent comprehensive genomic analysis focusing on loss of heterozygosity, p53 deletion/mutation, and other…
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2007
2007
Flt3 receptor tyrosine kinase in AML and its modulation of the p53/Hdm2/Bcl-2 pathway
Line Wergeland
2007
Corpus ID: 59487291
Background: Acute myeloid leukemia (AML) cells are characterized by non-mutated TP53, high levels of Hdm2, and frequent mutation…
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2006
2006
Advances in Brief p 53 Mutation and MDM 2 Amplification in Human Soft Tissue Sarcomas 1
F. Leach
,
T. Tokino
,
+7 authors
B. Vogelstein
2006
Corpus ID: 29786232
The p53 and MDM2 genes were analyzed in 24 human soft tissue sarcomas (11 malignant fibrous histiocytomas and 13 liposarcomas…
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2005
2005
Prognostic impact of vascular density and fibrosis in the bone marrow of children with high-risk acute lymphoblastic leukemia
U. Norén-Nyström
,
Göran Roos
,
Anders Bergh
,
Erik Forestier
Leukemia
2005
Corpus ID: 19515883
Prognostic impact of vascular density and fibrosis in the bone marrow of children with high-risk acute lymphoblastic leukemia.
Review
2004
Review
2004
MDM 2 and Prognosis
K. Onel
,
C. Cordon-Cardo
2004
Corpus ID: 1624494
The cellular stress response pathway regulated by the p53 tumor suppressor is critical to the maintenance of genomic integrity…
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