MDL 27048

Known as: 2-Propen-1-one, 1-(2,5-dimethoxyphenyl)-3-(4-(dimethylamino)phenyl)-2-methyl-, (E)-, MDL-27048 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2006
01219892006

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2006
2006
Although the structure has been elucidated for the binding of colchicine and podophyllotoxin as potent destabilizer for… (More)
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1998
1998
Distances between the paclitaxel, colchicine, and exchangeable GTP binding sites on tubulin polymers have been probed using… (More)
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1997
1997
Colchicide (IDE) is a colchicine (COL) analogue in which the C-10 methoxy group is replaced by a hydrogen atom. Its binding to… (More)
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1996
1996
The kinetics of the interaction of tubulin with two biphenyl analogues of colchicine were measured by fluorescence stopped flow… (More)
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1992
1992
MDL 27048 [trans-1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2- methyl-2-propen-1-one] fluoresces when bound to tubulin… (More)
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1992
1992
The kinetics of the binding of MDL 27048 to tubulin have been studied by fluorescence stopped flow. The binding is accompanied by… (More)
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1989
1989
We have characterized the binding of trans-1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methyl-2- propen- 1-one (MDL… (More)
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