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MDCO-216

National Institutes of Health

Papers overview

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2019
2019
The risk of heart failure (HF) is prominently increased in patients with type 2 diabetes mellitus. The objectives of this study… 
Highly Cited
2018
Highly Cited
2018
Importance Infusing a high-density lipoprotein mimetic containing apolipoprotein A-I Milano demonstrated potential atheroma… 
2018
2018
The pleiotropic properties of HDL may exert beneficial effects on the myocardium. The effect of recombinant HDLMilano on… 
2017
2017
PurposeAim of this study was to demonstrate that MDCO-216 (human recombinant Apolipoprotein A-I Milano) does not induce adverse… 
2017
2017
Reverse lipid transport is critical to maintain homeostasis. Smoking causes lipid accumulation in macrophages, therefore… 
Highly Cited
2016
Highly Cited
2016
Aims Apolipoprotein A-1 (ApoA-1), based on epidemiology, is inversely associated with cardiovascular (CV) events. Human carriers… 
2016
2016
Objective— To determine effects of single ascending doses of MDCO-216 on high-density lipoprotein (HDL) subfractions in relation… 
2014
2014
MDCO-216 is a complex of dimeric ApoA-IMilano and palmitoyl oleoyl phosphatidylcholine (POPC), previously shown to reduce… 
2013
2013
MDCO-216, a complex of dimeric recombinant apoA-IMilano (apoA-IM) and palmitoyl-oleoyl-phosphatidylcholine (POPC), was…