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MDC1 wt Allele
Known as:
Em:AB023051.5
, NFBD1
, KIAA0170
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Human MDC1 wild-type allele is located in the vicinity of 6p21.3 and is approximately 18 kb in length. This allele, which encodes mediator of DNA…
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National Institutes of Health
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Related topics
Related topics
2 relations
Cell Cycle Control
Broader (1)
MDC1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
NFBD1/MDC1 participates in the regulation of proliferation and apoptosis in human laryngeal squamous cell carcinoma
X. Liu
,
Z. Qiu
,
+9 authors
G. Hu
Clinical and Translational Oncology
2018
Corpus ID: 4062701
PurposeThe objective of the study was to investigate the role of NFBD1 in the proliferation and apoptosis of laryngeal squamous…
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2013
2013
NFBD1/MDC1 Is Phosphorylated by PLK1 and Controls G2/M Transition through the Regulation of a TOPOIIα-Mediated Decatenation Checkpoint
K. Ando
,
T. Ozaki
,
T. Hirota
,
A. Nakagawara
PLoS ONE
2013
Corpus ID: 17875678
Although it has been established that nuclear factor with BRCT domain 1/ mediator of the DNA damage checkpoint protein 1 (NFBD1…
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2013
2013
Expressions of NFBD1 in nasopharyngeal carcinoma and their clinical significances
Hu Guohua
2013
Corpus ID: 88929420
Objective:To investigate the expressions of nuclear factor with BRCT domain 1(NFBD1)in nasopharyngeal carcinoma and their…
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2011
2011
NFBD1/MDC1 is a protein of oncogenic potential in human cervical cancer
Chengfu Yuan
,
Y. Bu
,
+7 authors
Fangzhou Song
Molecular and Cellular Biochemistry
2011
Corpus ID: 16067442
A large nuclear protein of 2089 amino acids, NFBD1/MDC1 has recently been implicated in tumorigenesis and tumor growth. In this…
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2011
2011
NFBD1/MDC1 Regulates Cav1 and Cav2 Independently of DNA Damage and p53
Kathleen A. Wilson
,
S. Colavito
,
+4 authors
D. Stern
Molecular Cancer Research
2011
Corpus ID: 11691206
NFBD1/MDC1 is involved in DNA damage checkpoint signaling and DNA repair. NFBD1 binds to the chromatin component γH2AX at sites…
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2011
2011
NFBD 1 / MDC 1 Regulates Cav 1 and Cav 2 Independently of DNA Damage and p 53
Kathleen A. Wilson
,
S. Colavito
,
+4 authors
D. Stern
2011
Corpus ID: 26596399
NFBD1/MDC1 is involved in DNA damage checkpoint signaling and DNA repair. NFBD1 binds to the chromatin component gH2AX at sites…
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2010
2010
NFBD1/MDC1 participates in the regulation of G2/M transition in mammalian cells.
Y. Bu
,
Yusuke Suenaga
,
+5 authors
T. Ozaki
Biochemical and Biophysical Research…
2010
Corpus ID: 43435470
2010
2010
Growth inhibition, morphology change, and cell cycle alterations in NFBD1-depleted human esophageal cancer cells
Zhengmei Yang
,
Y. Bu
,
Changdong Wang
,
Geli Liu
,
Fangzhou Song
Molecular and Cellular Biochemistry
2010
Corpus ID: 27389033
NFBD1/MDC1 is a large nuclear protein mainly participating in DNA damage response, indicating its therapeutic potential as a…
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2007
2007
Sp1‐mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in DNA damage response pathway
Y. Bu
,
Yusuke Suenaga
,
+4 authors
T. Ozaki
Genes to Cells
2007
Corpus ID: 19288970
NFBD1/MDC1 is a large nuclear protein with an anti‐apoptotic potential which participates in DNA damage response. Recently, we…
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Highly Cited
2003
Highly Cited
2003
NFBD1/KIAA0170 Is a Chromatin-associated Protein Involved in DNA Damage Signaling Pathways*
Xingzhi Xu
,
D. Stern
Journal of Biological Chemistry
2003
Corpus ID: 20438307
NFBD1/KIAA0170 is a nuclearfactor with an N-terminal FHA (forkhead-associated) domain and a tandem repeat of BRCT (breastcancer…
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