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MCL1 protein, human
Known as:
Bcl-2-Related Protein EAT/mcl1
, mcl1/EAT
, MCL1L protein, human
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Induced myeloid leukemia cell differentiation protein Mcl-1 (350 aa, ~37 kDa) is encoded by the human MCL1 gene. This protein is involved in the…
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National Institutes of Health
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Related topics
Related topics
12 relations
Apoptosis
Apoptosis Inhibitor
BH1 Domain
BH2 Domain
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Broader (1)
Myeloid Cell Leukemia Sequence 1 Protein
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Regulation of MCL1 3' UTR-APA-derived mRNA isoforms
O. Kutsenko
2018
Corpus ID: 91822709
O trabalho desenvolvido nesta dissertacao foi financiado por fundos do Norte-01-0145-FEDER-000008 – “Porto Neurosciences and…
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Review
2017
Review
2017
The anti-apoptotic protein MCL1, a novel target of lung cancer therapy
Wataru Nakajima
,
N. Tanaka
,
Blockquote
2017
Corpus ID: 52268793
Evasion of apoptosis is one of the typical hallmarks of cancer and a major mechanism for cancer development, tumor growth, and…
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2017
2017
Targeting MCL1 dependent cancers by CDK9 inhibition
D. Bearss
2017
Corpus ID: 116878353
2016
2016
Targeting sphingosine kinase 1 induces MCL 1 dependent cell death in acute myeloid leukemia Running title : Targeting sphingosine kinase 1 in acute myeloid leukemia
J. Powell
,
Alexander C Lewis
,
+17 authors
S. Pitson
2016
Corpus ID: 24595565
Jason A. Powell, Alexander C. Lewis, Wenying Zhu, John Toubia, Melissa R. Pitman, Craig T. Wallington-Beddoe, Paul A. B. Moretti…
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Review
2016
Review
2016
Abstract 420: Translational strategy for targeting MCL1 amplified tumors with CDK9 inhibitor
Ziping Yang
,
Richard J. Bellin
,
P. Hessler
,
Xin Lu
,
T. Uziel
,
L. Lam
2016
Corpus ID: 78381221
BCL-2, BCL-XL, and MCL-1 are members of the prosurvival family of proteins that regulate the mitochondrial apoptotic pathway…
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2016
2016
Abstract P5-03-14: MLN0128 regulates survival signaling by AKT and its downstream effectors in HER2+ breast cancer model
P. De
,
J. Carlson
,
+4 authors
B. Leyland-Jones
2016
Corpus ID: 57592385
Evading apoptosis is considered to be a hallmark of cancers including breast cancer, since mutations in apoptotic regulators…
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2015
2015
Title Epigenetic silencing of tumor suppressor miR-3151 contributes to Chinese chronic lymphocytic leukemia by constitutive activation of MADD/ERK and PIK3R2/AKT signaling pathways
Lu-Qiang Wang
,
K. Wong
,
A. Rosén
,
C. Chim
2015
Corpus ID: 54778605
We hypothesize that miR-3151, localized to a GWAS-identified chronic lymphocytic leukemia (CLL) risk locus (8q22.3), is a tumor…
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2015
2015
[The myeloid cell leukemia-1 mRNA splicing mediated by epithelial splicing regulatory protein 1 (ESRP1) in glioma U251 cell lines].
Dayong Song
,
Zhiqiang Li
,
Z. Quan
,
Jun Zhao
,
Dayuan Xu
,
Ning Zhang
Xi bao yu fen zi mian yi xue za zhi = Chinese…
2015
Corpus ID: 42965510
OBJECTIVE To investigate the regulatory mechanism of myeloid cell leukemia-1 (MCL1) mRNA splicing mediated by epithelial splicing…
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2011
2011
Anti-apoptotic Bcl-xL and MCL 1 Proteins Cell Dedifferentiation and Dependence on Oncogene-induced Senescence Leads to Escape from p 21-mediated Signal Transduction :
Sophie de Carné Trécesson
,
Y. Guillemin
,
+7 authors
O. Coqueret
2011
Corpus ID: 207856633
2007
2007
Therapeutic Conversion of Viability Promoting MCL1 to Death-Inducing Forms: A Novel Strategy for Breast Cancer
R. W. Craig
2007
Corpus ID: 83188056
Abstract : The BCL2 family member MCL1 is expressed in breast cancer cells in its full-length, anti-apoptotic form. The goal of…
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