MC1R gene

Known as: MELANOCORTIN 1 RECEPTOR, MELANOCYTE-STIMULATING HORMONE RECEPTOR, MC1R 
This gene plays a role in epidermal development and regulation of melanogenesis.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Melanocortin-1-receptor (MC1R) is one of the major genes that determine skin pigmentation. MC1R variants were suggested to be… (More)
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Review
2005
Review
2005
Melanins are a ubiquitous component of plumage colouration in birds and serve a wide variety of functions. Although the genetic… (More)
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Highly Cited
2003
Highly Cited
2003
The relationships between MC1R gene variants and red hair, skin reflectance, degree of freckling and nevus count were… (More)
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Highly Cited
2001
Highly Cited
2001
Individuals carrying melanocortin 1 receptor gene variants have an increased risk for the development of cutaneous melanoma… (More)
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Review
2001
Review
2001
The synthesis of the visible pigment melanin by the melanocyte cell is the basis of the human pigmentary system, those genes… (More)
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Highly Cited
2001
Highly Cited
2001
Mutations in the exons of the cyclin-dependent kinase inhibitor gene CDKN2A are melanoma-predisposition alleles which have high… (More)
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Highly Cited
2000
Highly Cited
2000
It is widely assumed that genes that influence variation in skin and hair pigmentation are under selection. To date, the… (More)
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Review
2000
Review
2000
The melanocortin 1 receptor, a seven pass transmembrane G protein coupled receptor, is a key control point in melanogenesis. Loss… (More)
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Highly Cited
1998
Highly Cited
1998
The melanocortin receptor 1 (MC1R) plays a central role in regulation of eumelanin (black/brown) and phaeomelanin (red/yellow… (More)
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Highly Cited
1995
Highly Cited
1995
Melanin pigmentation protects the skin from the damaging effects of ultraviolet radiation (UVR). There are two types of melanin… (More)
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