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MBOAT2 protein, human
Known as:
Lysophospholipid Acyltransferase 2
, O-Acyltransferase Domain-Containing Protein 2
, Lysophosphatidylethanolamine Acyltransferase
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Lysophospholipid acyltransferase 2 (520 aa, ~60 kDa) is encoded by the human MBOAT2 gene. This protein is involved in lysophospholipid metabolism.
National Institutes of Health
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Related topics
Related topics
13 relations
Broader (1)
1-acylglycerol-3-phosphate O-acyltransferase
Enzyme Gene
Glycerolipid Metabolism Pathway
Integral Membrane Proteins
MBOAT2 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Lysophosphatidylcholine Acyltransferase 3 Is the Key Enzyme for Incorporating Arachidonic Acid into Glycerophospholipids during Adipocyte Differentiation
M. Eto
,
H. Shindou
,
A. Koeberle
,
T. Harayama
,
Keisuke Yanagida
,
Takao Shimizu
International journal of molecular sciences
2012
Corpus ID: 10608611
Cellular membranes contain glycerophospholipids, which have important structural and functional roles in cells…
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2012
2012
YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis
Sophie Ayciriex
,
M. Le Guédard
,
+10 authors
E. Testet
Molecular biology of the cell
2012
Corpus ID: 8556546
LOA1, a yeast member of the glycerolipid acyltransferase family, encodes a novel lysophosphatidic acid acyltransferase associated…
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Review
2008
Review
2008
Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids.
J. Vance
Journal of lipid research
2008
Corpus ID: 1906849
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are two aminophospholipids whose metabolism is interrelated. Both…
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Highly Cited
2008
Highly Cited
2008
Molecular Identification of a Novel Mammalian Brain Isoform of Acyl-CoA:Lysophospholipid Acyltransferase with Prominent Ethanolamine Lysophospholipid Acylating Activity, LPEAT2*
Jingsong Cao
,
Dandan Shan
,
+5 authors
R. Gimeno
Journal of Biological Chemistry
2008
Corpus ID: 12728779
Acyl-CoA-dependent lysophospholipid acyltransferases play an important role in attaining the appropriate molecular species of…
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Highly Cited
2007
Highly Cited
2007
Identification and Characterization of the Major Lysophosphatidylethanolamine Acyltransferase in Saccharomyces cerevisiae*
W. Riekhof
,
James Wu
,
Jennifer L. Jones
,
D. Voelker
Journal of Biological Chemistry
2007
Corpus ID: 36410243
We recently demonstrated that yeast actively import lysophosphatidylethanolamine (lyso-PtdEtn) through the action of plasma…
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2006
2006
Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival.
C. Diefenbach
,
R. Soslow
,
+7 authors
J. Dupont
Cancer
2006
Corpus ID: 24979451
BACKGROUND Lysophosphatidic acid acyltransferase-beta (LPAAT-beta) tumor expression is an emerging prognostic, diagnostic, and…
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Highly Cited
2003
Highly Cited
2003
Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma.
T. Hideshima
,
D. Chauhan
,
+11 authors
K. Anderson
Cancer research
2003
Corpus ID: 23584202
In this study, we examined the effects of isoform-specific functional inhibitors of lysophosphatidic acid acyltransferase (LPAAT…
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Highly Cited
1999
Highly Cited
1999
Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction.
T. M. Lewin
,
P. Wang
,
R. Coleman
Biochemistry
1999
Corpus ID: 12051900
Alignment of amino acid sequences from various acyltransferases [sn-glycerol-3-phosphate acyltransferase (GPAT), lysophosphatidic…
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1998
1998
Biosynthesis of C18 polyunsaturated fatty acids in microsomal membrane preparations from the filamentous fungus Mucor circinelloides.
F. Jackson
,
T. Fraser
,
M. Smith
,
C. Lazarus
,
A. Stobart
,
G. Griffiths
European journal of biochemistry
1998
Corpus ID: 21212681
The biosynthesis of C18 polyunsaturated fatty acids has been studied in the fungus Mucor circinelloides. Microsomal membrane…
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Highly Cited
1997
Highly Cited
1997
Human Lysophosphatidic Acid Acyltransferase
C. Eberhardt
,
P. Gray
,
L. Tjoelker
The Journal of Biological Chemistry
1997
Corpus ID: 31465493
Lysophosphatidic acid (1-acyl-sn-glycero-3-phosphate (LPA)) is a phospholipid with diverse biological activities. The mediator…
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