FAQ

MBOAT2 protein, human

Known as: Lysophospholipid Acyltransferase 2, O-Acyltransferase Domain-Containing Protein 2, Lysophosphatidylethanolamine Acyltransferase 
Lysophospholipid acyltransferase 2 (520 aa, ~60 kDa) is encoded by the human MBOAT2 gene. This protein is involved in lysophospholipid metabolism.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0519842018

Related topics

Related topics

14 relations

Broader (1)

1-acylglycerol-3-phosphate O-acyltransferase
Enzyme GeneGlycerolipid Metabolism PathwayIntegral Membrane ProteinsMBOAT2 gene
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
MBOAT2 protein, human
neutrophil
Integral Membrane Proteins
Transmembrane Domain
Phospholipid Metabolism
Phosphatidylcholine Biosynthesis

Papers overview

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Highly Cited
2012
Highly Cited
2012
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Numerous studies in humans link a nonsynonymous genetic polymorphism (I148M) in adiponutrin (ADPN) to various forms of fatty… (More)
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2010
2010
Expression of rapeseed microsomal lysophosphatidic acid acyltransferase isozymes enhances seed oil content in Arabidopsis.
In higher plants, lysophosphatidic acid acyltransferase (LPAAT), located in the cytoplasmic endomembrane compartment, plays an… (More)
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2010
2010
CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase.
Mutations in human CGI-58/ABHD5 cause Chanarin-Dorfman syndrome (CDS), characterized by excessive storage of triacylglycerol in… (More)
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2008
2008
Molecular identification of a novel mammalian brain isoform of acyl-CoA:lysophospholipid acyltransferase with prominent ethanolamine lysophospholipid acylating activity, LPEAT2.
Acyl-CoA-dependent lysophospholipid acyltransferases play an important role in attaining the appropriate molecular species of… (More)
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Highly Cited
2007
Highly Cited
2007
Identification and characterization of the major lysophosphatidylethanolamine acyltransferase in Saccharomyces cerevisiae.
We recently demonstrated that yeast actively import lysophosphatidylethanolamine (lyso-PtdEtn) through the action of plasma… (More)
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2006
2006
Substrate specificity of lysophosphatidic acid acyltransferase beta -- evidence from membrane and whole cell assays.
Membranes of mammalian cells contain lysophosphatidic acid acyltransferase (LPAAT) activities that catalyze the acylation of sn-1… (More)
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2004
2004
Loss of plastidic lysophosphatidic acid acyltransferase causes embryo-lethality in Arabidopsis.
Phosphatidic acid is a key intermediate for chloroplast membrane lipid biosynthesis. De novo phosphatidic acid biosynthesis in… (More)
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2003
2003
Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma.
In this study, we examined the effects of isoform-specific functional inhibitors of lysophosphatidic acid acyltransferase (LPAAT… (More)
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Highly Cited
1999
Highly Cited
1999
Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction.
Alignment of amino acid sequences from various acyltransferases [sn-glycerol-3-phosphate acyltransferase (GPAT), lysophosphatidic… (More)
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1997
1997
Human lysophosphatidic acid acyltransferase. cDNA cloning, expression, and localization to chromosome 9q34.3.
Lysophosphatidic acid (1-acyl-sn-glycero-3-phosphate (LPA)) is a phospholipid with diverse biological activities. The mediator… (More)
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