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MBD3 gene

Known as: METHYL-CpG-BINDING DOMAIN PROTEIN 3, MBD3, Methyl-CpG Binding Domain Protein 3 Gene 
This gene is involved in DNA methylation, histone deacetylation and transcriptional regulation.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Summary The Nucleosome Remodeling and Deacetylase (NuRD) complex is essential for embryonic development and pluripotent stem cell… Expand
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Highly Cited
2013
Highly Cited
2013
The Mi-2/nucleosome remodeling and histone deacetylase (NuRD) complex is a multiprotein machine proposed to regulate chromatin… Expand
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Highly Cited
2013
Highly Cited
2013
The heterogeneous collection of nucleosome remodelling and deacetylation (NuRD) complexes can be grouped into the MBD2- or MBD3… Expand
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Highly Cited
2007
Highly Cited
2007
Mbd3 is a core component of the NuRD (Nucleosome Remodeling and Histone Deacetylation) co-repressor complex, and NuRD-mediated… Expand
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Highly Cited
2007
Highly Cited
2007
Paternal repression of the imprinted H19 gene is mediated by a differentially methylated domain (DMD) that is essential to… Expand
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Highly Cited
2002
Highly Cited
2002
Although mammalian MBD3 contains the mCpG-binding domain (MBD) and is highly homologous with the authentic mCpG-binding protein… Expand
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Highly Cited
2001
Highly Cited
2001
MBD2 and MBD3 are closely related proteins with consensus methyl-CpG binding domains. MBD2 is a transcriptional repressor that… Expand
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Highly Cited
1999
Highly Cited
1999
ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation represent mechanisms to alter nucleosome… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract. DNA methylation is essential for murine development and is implicated in the control of gene expression. MeCP2, MBD1… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT Methylation at the DNA sequence 5′-CpG is required for mouse development. MeCP2 and MBD1 (formerly PCM1) are two known… Expand
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