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MB327

 
National Institutes of Health

Papers overview

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2018
2018
The bispyridinium compound MB327 has been shown previously to have a positive pharmacological effect against poisoning with… Expand
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2018
2018
Medical countermeasures for acute poisoning by organophosphorus nerve agents are generally assessed over 24h following poisoning… Expand
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2018
2018
The primary toxic mechanism of organophosphorus compounds, i.e. nerve agents or pesticides, is based on the irreversible… Expand
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2018
2018
Irreversible inhibition of the acetylcholine esterase upon intoxication with organophosphorus compounds leads to an accumulation… Expand
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2018
2018
A novel series of 30 symmetric bispyridinium and related N-heteroaromatic bisquaternary salts with a propane-1,3-diyl linker was… Expand
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2016
2016
Abstract The potency of the bispyridinium non-oxime compound MB327 [1,1′-(propane-1,3-diyl)bis(4-tert-butylpyridinium) diiodide… Expand
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2016
2016
Current organophosphorus nerve agent medical countermeasures do not directly address the nicotinic effects of poisoning. A series… Expand
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2013
2013
Organophosphorous compounds (OP) are highly toxic compounds. Great efforts have been undertaken in the last decades to develop… Expand
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2012
2012
The standard treatment of poisoning by organophosphorus (OP) nerve agents with atropine and oximes is not sufficiently effective… Expand
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