MAVS gene

Known as: VISA, IFNB PROMOTER STIMULATOR 1, IPS1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2018
0102019932018

Papers overview

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Highly Cited
2013
Highly Cited
2013
RNA virus infections are detected by the RIG-I family of receptors, which induce type-I interferons through the mitochondrial… (More)
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Highly Cited
2010
Highly Cited
2010
Retinoic acid-inducible gene-I (RIG-I)-like receptors (RLR) are members of the DEAD box helicases, and recognize viral RNA in the… (More)
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2010
2010
Cross-talk between NK cells and dendritic cells (DCs) is critical for the potent therapeutic response to dsRNA, but the receptors… (More)
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2009
2009
NLRX1 is the only member of the Nod-like receptor (NLR) family that is targeted to the mitochondria, and its overexpression… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Host responses to viral infection include both immune activation and programmed cell death. The mitochondrial… (More)
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2007
2007
IPS-1/MAVS/VISA/Cardif is an adaptor protein that plays a crucial role in the induction of interferons in response to viral… (More)
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Highly Cited
2006
Highly Cited
2006
The mitochondrial antiviral signaling protein (MAVS) mediates the activation of NFkappaB and IRFs and the induction of… (More)
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Highly Cited
2006
Highly Cited
2006
Upon recognition of viral infection, RIG-I and Helicard recruit a newly identified adapter termed Cardif, which induces type I… (More)
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Highly Cited
2006
Highly Cited
2006
Intracellular RNA virus infection is detected by the cytoplasmic RNA helicase RIG-I that plays an essential role in signaling to… (More)
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Highly Cited
2005
Highly Cited
2005
Antiviral immunity against a pathogen is mounted upon recognition by the host of virally associated structures. One of these… (More)
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