Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

MARCKS gene

Known as: myristoylated alanine rich protein kinase C substrate, PKCSL, Myristoylated Alanine-rich Protein Kinase C Substrate Gene 
This gene plays a role in actin filament crosslinking.
National Institutes of Health

Related topics

Related topics

5 relations
Cell MovementCytokinesisMARCKS protein, humanMuscle Contraction
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma
Multiple myeloma (MM) is incurable in virtually all patients due to the presence of innate and emergent drug-resistance. To… 
  • figure 1
  • figure 2
  • figure 3
  • figure 3
  • figure 4
2013
2013
The Design of MACs (Minimal Actin Cortices)
The actin cell cortex in eukaryotic cells is a key player in controlling and maintaining the shape of cells, and in driving major… 
2013
2013
Myristoylated Alanine-Rich protein Kinase C Substrate (MARCKS) expression modulates the metastatic phenotype in human and murine colon carcinoma in vitro and in vivo.
Several actin-binding proteins have been shown to be altered in metastatic cell lines and tumours and, in particular… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2010
Highly Cited
2010
Cardiomyogenic Potential of C-Kit+–Expressing Cells Derived From Neonatal and Adult Mouse Hearts
Background— C-kit is a receptor tyrosine kinase family member expressed in hematopoietic stem cells. C-kit is also transiently… 
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Review
2000
Review
2000
Mouse models for neural tube closure defects.
Neural tube closure defects (NTDs), in particular anencephaly and spina bifida, are common human birth defects (1 in 1000), their… 
  • table 1
  • table 1
  • table 2
  • figure 1
Highly Cited
1995
Highly Cited
1995
Dephosphorylation of protein kinase C substrates, neurogranin, neuromodulin, and MARCKS, by calcineurin and protein phosphatases 1 and 2A.
Neurogranin, neuromodulin, and MARCKS are among the most prominent substrates of protein kinase C (PKC) in the mammalian brain… 
Highly Cited
1995
Highly Cited
1995
The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C.
The myristoylated alanine-rich C-kinase substrate (MARCKS) is the major protein kinase C (PKC) substrate in many cell types… 
Highly Cited
1992
Highly Cited
1992
Effect of myristoylation on p27 nef subcellular distribution and suppression of HIV-LTR transcription.
The effect of myristoylation on p27nef subcellular distribution and suppression of HIV-1 transcription was examined by… 
1991
1991
A mouse brain cDNA encodes a novel protein with the protein kinase C phosphorylation site domain common to MARCKS
We have isolated a mouse brain cDNA clone encoding a protein of 200 amino acids (M r, 20165) with partial homology with MARCKS… 
Highly Cited
1991
Highly Cited
1991
The human myristoylated alanine-rich C kinase substrate (MARCKS) gene (MACS). Analysis of its gene product, promoter, and chromosomal localization.
The expression of a major cellular substrate for protein kinase C, the MARCKS protein, is regulated in a cell-, tissue-, and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE