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MAP3K7 protein, human

Known as: MAP3K7, TAK1 protein, human, TGF-Beta-Activated Kinase 1 
Mitogen-activated protein kinase kinase kinase 7 (606 aa, ~67 kDa) is encoded by the human MAP3K7 gene. This protein plays a role in both serine… 
National Institutes of Health

Related topics

Related topics

34 relations
ALK PathwayApoptosisB-Cell Immune Response PathwayBMP Receptor Signaling Pathway

Broader (1)

MAP kinase kinase kinase 7

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MicroRNA-143 inhibits cell growth by targeting ERK5 and MAP3K7 in breast cancer
This study aimed to investigate the function and mechanism of microRNA-143 (miR-143) in the occurrence and development of breast… 
Highly Cited
2016
Highly Cited
2016
The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis
Tripartite motif 8 (TRIM8), an E3 ligase ubiquitously expressed in various cells, is closely involved in innate immunity. However… 
2016
2016
Effect of curcumin (Curcuma longa extract) on LPS-induced acute lung injury is mediated by the activation of AMPK
PurposeCurcumin, a biphenolic compound extracted from turmeric (Curcuma longa), possesses potent anti-inflammatory activity. The… 
Highly Cited
2009
Highly Cited
2009
TAK1 is an essential regulator of BMP signalling in cartilage
TGFβ activated kinase 1 (TAK1), a member of the MAPKKK family, controls diverse functions ranging from innate and adaptive immune… 
2009
2009
Human T Cell Lymphotropic Virus 1 Manipulates Interferon Regulatory Signals by Controlling the TAK1-IRF3 and IRF4 Pathways*
We previously reported that human T cell lymphotropic virus 1 (HTLV-1) Tax oncoprotein constitutively activates transforming… 
Highly Cited
2006
Highly Cited
2006
The TGF beta activated kinase TAK1 regulates vascular development in vivo.
TGFbeta activated kinase 1 (TAK1) is a MAPKKK that in cell culture systems has been shown to act downstream of a variety of… 
Highly Cited
2004
Highly Cited
2004
Nucleotide-binding Oligomerization Domain Proteins Are Innate Immune Receptors for Internalized Streptococcus pneumoniae*
Streptococcus pneumoniae, the major cause of community-acquired pneumonia and bacterial meningitis, has been shown to transiently… 
2003
2003
p38 MAPK Is Involved in Activin A- and Hepatocyte Growth Factor-mediated Expression of Pro-endocrine Gene Neurogenin 3 in AR42J-B13 Cells*
Neurogenin3 (ngn3) is a transcription factor that is essential for the differentiation of pancreatic endocrine cells. To… 
2001
2001
TAK1 activation of the mouse JunB promoter is mediated through a CCAAT box and NF‐Y
2001
2001
Helicobacter pylori lipopolysaccharide induces apoptosis of cultured guinea pig gastric mucosal cells.
Helicobacter pylori lipopolysaccharide (LPS) is generally accepted as a low-toxicity virulence. Primary cultures of guinea pig… 
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