MAP3K13 protein, human

Known as: leucine zipper-bearing kinase protein, human, MLK, Mitogen-Activated Protein Kinase Kinase Kinase 13 
Mitogen-activated protein kinase kinase kinase 13 (966 aa, ~108 kDa) is encoded by the human MAP3K13 gene. This protein is involved in the mediation… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Necroptosis is a form of regulated cell death, which is induced by ligand binding to TNF family death domain receptors, pattern… (More)
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Review
2016
Review
2016
The accumulation of lipids is a histologic and biochemical hallmark of obesity-associated nonalcoholic fatty liver disease (NAFLD… (More)
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Highly Cited
2014
Highly Cited
2014
The mixed lineage kinase domain-like protein (MLKL) has recently been identified as a key RIP3 (receptor interacting protein 3… (More)
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Review
2014
Review
2014
Cell death research was revitalized by the understanding that necrosis can occur in a highly regulated and genetically controlled… (More)
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Highly Cited
2014
Highly Cited
2014
Programmed necrotic cell death induced by the tumor necrosis factor alpha (TNF-α) family of cytokines is dependent on a kinase… (More)
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Highly Cited
2014
Highly Cited
2014
Mixed lineage kinase domain-like protein (MLKL) was identified to function downstream of receptor interacting protein 3 (RIP3) in… (More)
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Highly Cited
2014
Highly Cited
2014
Although mixed lineage kinase domain-like (MLKL) protein has emerged as a specific and crucial protein for necroptosis induction… (More)
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Highly Cited
2012
Highly Cited
2012
The receptor-interacting serine-threonine kinase 3 (RIP3) is a key signaling molecule in the programmed necrosis (necroptosis… (More)
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Highly Cited
2012
Highly Cited
2012
The programmed necrosis induced by TNF-α requires the activities of the receptor-interacting serine-threonine kinases RIP1 and… (More)
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Highly Cited
2012
Highly Cited
2012
Tumor necrosis factor (TNF) is an important inflammatory cytokine and induces many cellular responses, including inflammation… (More)
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