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MAP3K1 protein, human
Known as:
MEK Kinase 1
, mitogen-activated protein kinase kinase kinase 1, human
, MEKK 1
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Mitogen-activated protein kinase kinase kinase 1 (1512 aa, ~164 kDa) is encoded by the human MAP3K1 gene. This protein plays a role in signal…
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National Institutes of Health
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Related topics
Related topics
46 relations
Angiotensin II Signaling Pathway
B Cell Receptor Signaling Pathway
CD40L Signaling Pathway
EGF Signaling Pathway
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Broader (2)
MAP Kinase Kinase Kinase 1
MAPK-ERK Kinase Kinases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
MP13-08 RADIOGENOMIC DISSECTION OF MULTIFOCAL PROSTATE CANCER
S. Salami
,
J. Kaplan
,
+17 authors
G. Palapattu
Journal of Urology
2019
Corpus ID: 150215954
INTRODUCTION AND OBJECTIVES: Up to 20% of patients with negative multiparametric magnetic resonance imaging (MRI) harbor Gleason…
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2017
2017
Nonsense-associated altered splicing leading to a human disorder: Identification of MAP3K1 mutations in two brothers with 46,XY disorders of sex development
Maki Igarashi
,
K. Kinjo
,
R. Horikawa
,
T. Ogata
,
M. Fukami
2017
Corpus ID: 90747154
2016
2016
The Role of MAP3K1 in Luminal Subtype Breast Cancer
Samuel F Gilbert
2016
Corpus ID: 79949863
2016
2016
Abstract 240: Functional significance of co-occurring mutations in PIK3CA and MAP3K1 in breast cancer
Álvaro Avivar-Valderas
,
R. McEwen
,
+6 authors
F. Cruzalegui
2016
Corpus ID: 78918737
2016
2016
Abstract P3-07-41: Genomic alterations indicative of a luminal A subtype associate with clinical benefit to buparlisib and letrozole in endocrine-resistant ER+/HER2– metastatic breast cancer
J. Balko
,
Mellissa J. Hicks
,
+8 authors
C. Arteaga
2016
Corpus ID: 76803133
Background: Activation of the phosphoinositide-3-kinase (PI3K) pathway has been associated with resistance to endocrine therapy…
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2016
2016
Abstract P3-05-06: Evolution of genomic alterations on endocrine therapy and mTOR inhibition in estrogen receptor (ER)-positive breast cancer
S. Massarweh
,
E. Romond
,
+4 authors
E. Black
2016
Corpus ID: 76796174
Background: Endocrine therapy (ET) and mTOR inhibition are important treatment strategies in ER-positive breast cancer, but no…
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2016
2016
Abstract PD6-06: Somatic mutation patterns differentially affect survival in breast cancer molecular subtypes
Balázs Győrffy
,
L. Pongor
,
A. Szabó
,
G. Bottai
,
L. Pusztai
,
L. Santarpia
2016
Corpus ID: 77049480
Background: The prognostic effects of somatic gene mutations and correlated gene expression in breast cancer is argument of…
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2015
2015
Loss- and gain-of-function analyses of the role of MAP kinase signalling in testis determination
Madeleine Pope
2015
Corpus ID: 91050768
Sexual differentiation is the process by which an organism develops as either male or female. In mammals, this process is…
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1998
1998
Interplay Between CD3 and CD28 Signals and MEK Kinase 1 (MEKK1) May Mediate the by CD28 Signaling: p21-Activated Kinase (PAK) Activation of p21-CDC42/Rac-Activated Kinases
S. Kaga
,
S. Ragg
,
K. Rogers
,
A. Ochi
1998
Corpus ID: 10210996