MAP2K1 wt Allele

Known as: MEK1, MKK1, MAPKK1 
Human MAP2K1 wild-type allele is located within 15q22.1-q22.33 and is approximately 104 kb in length. This allele, which encodes mitogen-activated… (More)
National Institutes of Health

Papers overview

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2013
2013
Recent studies have reported that miR-181b contributes to chemoresistance in several cancer types and functions as a tumor… (More)
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2009
2009
Constitutive activation of the MAP kinase kinase MEK1 induces oncogenic transformation in intestinal epithelial cells. Loss of… (More)
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2008
2008
Toll-like receptor (TLR)-4 signaling promotes cytokine synthesis in vascular smooth muscle cells (VSMC). However, it is unknown… (More)
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2007
2007
BACKGROUND Among gynecologic cancers, ovarian cancer is the second most common and has the highest death rate. Cancer is a… (More)
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2004
2004
Epidermal activation of Erk MAPK is observed in human psoriatic lesions and in a mouse model of psoriasis in which beta1… (More)
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2004
2004
The ERK cascade is activated by hormones, cytokines, and growth factors that result in either proliferation or growth arrest… (More)
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2000
2000
The Raf/MEK/MAP kinase cascade plays a critical role in transducing growth signals from activated cell surface receptors. Using… (More)
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Highly Cited
1998
Highly Cited
1998
Clonal selection of T lymphocytes is essential for establishing self/non-self discrimination of immune recognition. It is known… (More)
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1998
1998
We have previously demonstrated that hydrogen peroxide (H2O2) treatment of bovine tracheal myocytes increases the activity of… (More)
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1997
1997
We tested whether activation of mitogen-activated protein kinase/ extracellular signal-regulated kinase kinase-1 (MEK1) is… (More)
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