MAP2K1 protein, human

Known as: ERK Activator Kinase 1, MEK 1, JNKK 
Dual specificity mitogen-activated protein kinase kinase 1 (393 aa, ~43 kDa) is encoded by the human MAP2K1 gene. This protein plays a role in… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Mitogen-activated protein kinase (MAPK) cascades play important roles in regulating plant innate immune responses. In a genetic… (More)
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Highly Cited
2006
Highly Cited
2006
Plants sense pathogens through both pathogen-associated molecular patterns and recognition of race-specific virulence factors… (More)
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Highly Cited
2001
Highly Cited
2001
Differentiated osteoclasts have a short life span. We tested various cytokines and growth factors for the effects on the survival… (More)
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Highly Cited
1999
Highly Cited
1999
Raf-1 phosphorylates and activates MEK-1, a kinase that activates the extracellular signal regulated kinases (ERK). This kinase… (More)
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Highly Cited
1998
Highly Cited
1998
The p42/44 mitogen-activated protein (MAP)-kinase cascade is a well-established signal transduction pathway that is initiated at… (More)
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Highly Cited
1998
Highly Cited
1998
Phorbol ester treatment of quiescent Swiss 3T3 cells leads to cell proliferation, a response thought to be mediated by protein… (More)
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Highly Cited
1998
Highly Cited
1998
The molecular signaling mechanisms by which muscle contractions lead to changes in glucose metabolism and gene expression remain… (More)
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Highly Cited
1995
Highly Cited
1995
The RHO1 gene in Saccharomyces cerevisiae encodes a homolog of the mammalian RhoA small GTP-binding protein, which is implicated… (More)
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Highly Cited
1994
Highly Cited
1994
A KINASE distinct from the MEK activator Raf1–3, termed MEK kinase-1 (MEKK), was originally identified by virtue of its homo-logy… (More)
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Highly Cited
1993
Highly Cited
1993
The PKC1 gene of Saccharomyces cerevisiae encodes a homolog of mammalian protein kinase C that is required for normal growth and… (More)
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