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MAP1LC3B gene

Known as: Microtubule-Associated Protein 1 Light Chain 3 Beta Gene, MICROTUBULE-ASSOCIATED PROTEIN 1, LIGHT CHAIN 3, BETA, LC3B 
This gene is involved in the formation of autophagosomal vacuoles.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Accumulation of β-amyloid (Aβ) and resultant inflammation are critical pathological features of Alzheimer disease (AD). Microglia… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND & AIMS Intestinal epithelial cells aid in mucosal defense by providing a physical barrier against entry of pathogenic… Expand
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Highly Cited
2012
Highly Cited
2012
Mechanisms by which autophagy promotes cell survival or death are unclear. We provide evidence that C18-pyridinium ceramide (C18… Expand
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Highly Cited
2011
Highly Cited
2011
Autophagy, a cellular process for organelle and protein turnover, regulates innate immune responses. Here we demonstrate that… Expand
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Highly Cited
2010
Highly Cited
2010
Tumor hypoxia is a common microenvironmental factor that adversely influences tumor phenotype and treatment response. Cellular… Expand
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Highly Cited
2010
Highly Cited
2010
Macroautophagy (hereafter referred to as autophagy) is a catabolic pathway to isolate and transport cytosolic components to the… Expand
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Highly Cited
2008
Highly Cited
2008
Background Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by abnormal cellular… Expand
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Highly Cited
2008
Highly Cited
2008
Cigarette smoke-induced cell death contributes to the pathogenesis of chronic obstructive pulmonary disease, though the relative… Expand
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Highly Cited
2004
Highly Cited
2004
Human light chain 3/MAP1LC3B, an autophagosomal ortholog of yeast Atg8, is conjugated to phospholipid (PL) via ubiquitylation… Expand
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Highly Cited
2003
Highly Cited
2003
The molecular machinery required for autophagy is highly conserved in all eukaryotes as seen by the high degree of conservation… Expand
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