MAP-kinase-activated kinase 2
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Senescent cells secrete a combination of factors collectively known as the senescence-associated secretory phenotype (SASP). The… Expand Probiotic bacteria are microorganisms that benefit the host through improvement of the balance of intestinal microflora and… Expand Myocardial ischemia and ischemia/reperfusion activate several protein kinase pathways. Protein kinase activation potentially… Expand Stress granules (SGs) are dynamic cytoplasmic foci at which stalled translation initiation complexes accumulate in cells… Expand Taxanes are widely used to treat malignancies and are known to modulate the transcription of several genes. We investigated the… Expand Interferons (IFNs) are pleiotropic cytokines that exhibit multiple biological effects on cells and tissues. IFN receptors are… Expand Most of the members of the superfamily of mammalian small heat shock or stress proteins are abundant in muscles where they play a… Expand We have investigated the activation of the p38 MAPK pathway in response to CD40 engagement in multiple B cell lines and in human… Expand Bacterial LPS stimulation of murine macrophages leads to increased tyrosine phosphorylation and activation of the 42- and 44-kDa… Expand An IL-1-stimulated protein kinase cascade resulting in phosphorylation of the small heat shock protein hsp27 has been identified… Expand