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MAP Kinase Kinase Kinase 3

Known as: MAPK ERK Kinase Kinase 3, MAP3K3 Protein Kinase, MEK Kinase 3 
A 70-kDa MAPK kinase kinase with specificity for MAP KINASE KINASE 5.
National Institutes of Health

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In BloodMAP Kinase Kinase 3MAP3K3 geneProcess of secretion

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MAP3K3 protein, human

Papers overview

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2019
2019
Maternal Exposure to Nanoparticulate Titanium Dioxide Causes Inhibition of Hippocampal Development Involving Dysfunction of the Rho/NMDAR Signaling Pathway in Offspring.
Numerous studies have suggested that nano-TiO₂ can be translocated to the brain via the placental barrier and blood brain barrier… 
2017
2017
GTP binding controls complex formation by the human ROCO protein
2016
2016
Abstract 02: Pan-cancer analysis of hotspot mutations in genes encoding the members of mitogen activated protein kinase (MAPK) and phosphoinosidtide-3 kinase (PI3K) pathways among smokers and non…
Background: In lung cancer, the MAPK pathway is activated mainly by KRAS and EGFR mutations in smokers and non-smokers… 
2013
2013
The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes.
2013
2013
Analysis of Leucine-rich repeat kinase 2 (LRRK2) and Parkinson protein 2 (parkin, PARK2) genes mutations in Slovak Parkinson disease patients.
Parkinson disease (PD) is a chronic neurodegenerative movement disorder characterized by selective loss of nigrostriatal… 
2013
2013
Parkinsonism, dementia and glucocerebrosidase mutations
Objectives: Previous associations between mitochondrial DNA (mtDNA) and idiopathic Parkinson disease (PD) have been inconsistent… 
2010
2010
Mutations in the Parkinson's disease genes, Leucine Rich Repeat Kinase 2 (LRRK2) and Glucocerebrosidase (GBA), are not associated with essential tremor.
2009
2009
Dimerization 2 ( LRRK 2 ) Kinase Activity on Dependence of Leucine-rich Repeat Kinase Protein Structure and Folding :
2008
2008
Human immunodeficiency virus.
Microglia have been known to be the resident immune cells in the brain for quite some time, but their role as pathologic players… 
Highly Cited
1991
Highly Cited
1991
Identification of chicken embryo kinase 5, a developmentally regulated receptor-type tyrosine kinase of the Eph family.
Chicken embryo kinase 5 (Cek5) is a transmembrane tyrosine kinase of the Eph family that was identified by screening a 10-d… 
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