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MAP Kinase Kinase 1

Known as: MEK1 Protein Kinase, MKK 1 Protein Kinase, MAPK Kinase 1 
An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 1 and MITOGEN-ACTIVATED… 
National Institutes of Health

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In BloodMAP Kinase Kinase Kinase 1MAP2K1 geneProcess of secretion
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MAP2K1 protein, human

Papers overview

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Highly Cited
2017
Highly Cited
2017
Somatic MAP2K1 Mutations Are Associated with Extracranial Arteriovenous Malformation.
Review
2016
Review
2016
Quercetin and the mitochondria: A mechanistic view.
Review
2014
Review
2014
Detecting the spectrum of multigene mutations in non-small cell lung cancer by Snapshot assay
As molecular targets continue to be identified and more targeted inhibitors are developed for personalized treatment of non-small… 
2008
2008
Inhibition of Anthrax Lethal Toxin-Induced Cytolysis of RAW264.7 Cells by Celastrol
Background Bacillus anthracis is the bacterium responsible for causing anthrax. The ability of B. anthracis to cause disease is… 
2006
2006
Mitogen-Activated Protein Kinase Pathway Regulates Cell Proliferation in Venous Ulcer Fibroblasts
Venous ulcer fibroblasts have been demonstrated to have low growth rates in response to platelet-derived growth factor (PDGF… 
2005
2005
ERK1/2 is a negative regulator of homeodomain protein Arix/Phox2a
The homeodomain protein Arix/Phox2a plays a role in the development and maintenance of the noradrenergic cell type by regulating… 
2005
2005
Analisis Pelaksanaan Program Praktek PengalamanLapangan Mahasiswa Program Studi Pendidikan Akuntansi Jurusan Ekonomi Fakultas Ilmu Sosial Universitas Negeri Semarang.
Hasil PPL, merupakan suatu tolok ukur dalam keberhasilan pembentukan mental keguruan pada mahasiswa kependidikan, namun demikian… 
Highly Cited
2001
Highly Cited
2001
Chronic cocaine‐mediated changes in non‐human primate nucleus accumbens gene expression
Chronic cocaine use elicits changes in the pattern of gene expression within reinforcement‐related, dopaminergic regions. cDNA… 
Highly Cited
1999
Highly Cited
1999
Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts.
The mitogen-activated protein kinase (MAPK) cascade is required for mitogenesis in somatic mammalian cells and is activated by a… 
Highly Cited
1997
Highly Cited
1997
The p42/p44 Mitogen-activated Protein Kinase Cascade Is Determinant in Mediating Activation of the Na+/H+ Exchanger (NHE1 Isoform) in Response to Growth Factors*
The ubiquitously expressed Na+/H+ exchanger NHE1 is the target of multiple signaling pathways, including those activated by… 
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