MAJOR AFFECTIVE DISORDER 2

Known as: MAFD2, BIPOLAR AFFECTIVE DISORDER, MANIC-DEPRESSIVE ILLNESS 
 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Bipolar DisorderGenetic Diseases, X-Linked
MAFD1 geneMAJOR AFFECTIVE DISORDER 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy
Attempts to develop gene therapy for Duchenne muscular dystrophy (DMD) have been complicated by the enormous size of the… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers
Duchenne muscular dystrophy results from the lack of dystrophin, a cytoskeletal protein associated with the inner surface… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice
Dystrophin-deficient muscles experience large reductions in expression of nitric oxide synthase (NOS), which suggests that NO… (More)
  • figure 2
  • figure 1
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Expression of full-length utrophin prevents muscular dystrophy in mdx mice
Duchenne muscular dystrophy (DMD) is a lethal, progressive muscle wasting disease caused by a loss of sarcolemmal bound… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Animal Models for Muscular Dystrophy Show Different Patterns of Sarcolemmal Disruption
Genetic defects in a number of components of the dystrophin-glycoprotein complex (DGC) lead to distinct forms of muscular… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1996
Highly Cited
1996
MyoD is required for myogenic stem cell function in adult skeletal muscle.
To investigate the function of MyoD in adult skeletal muscle, we interbred MyoD mutant mice with mdx mice, a model for Duchenne… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase.
Adenoviral vector-mediated gene transfer offers significant potential for gene therapy of many human diseases. However, progress… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene
DUCHENNE muscular dystrophy (DMD) is a severe, progressive muscle-wasting disease that causes cardiac or respiratory failure1,2… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Dystrophin protects the sarcolemma from stresses developed during muscle contraction.
The protein dystrophin, normally found on the cytoplasmic surface of skeletal muscle cell membranes, is absent in patients with… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts
An important corollary to the recent advances in our understanding of the primary cause of Duchenne muscular dystrophy1–6, is the… (More)
Is this relevant?