Lysosome-Associated Membrane Glycoproteins

This review focuses on the pathways that regulate lysosome biogenesis and that are implicated in numerous degenerative storage… Expand

Lysosomes are acidic compartments in mammalian cells that are primarily responsible for the breakdown of endocytic and autophagic… Expand

Lysosomes are the primary catabolic compartments of eukaryotic cells. They degrade extracellular material that has been… Expand

Salmonella Typhimurium is a facultative intracellular pathogen that causes acute gastroenteritis in man. Intracellular Salmonella… Expand

We searched for novel proteins in lysosomal membranes, tentatively participating in molecular transport across the membrane and… Expand

The adaptor protein (AP) 3 adaptor complex has been implicated in the transport of lysosomal membrane proteins, but its precise… Expand

It has recently become clear that lysosomes have more complex functions than simply being the end-point on a degradative pathway… Expand

NRAMP2 (naturalresistance-associated macrophageprotein 2)/DMT1 (divalentmetal transporter 1) is a divalent metal transporter… Expand

AP-3 is a heterotetrameric protein complex involved in intracellular vesicle transport. Molecular analyses show that Ap3b1, which… Expand

We have used monospecific antisera to two lysosomal membrane glycoproteins, lgp120 and a similar protein, lgp110, to compare the… Expand