Loxapine

Known as: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine, 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz(b,f)(1,4)oxazepine, Dibenz(b,f)(1,4)oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)- 
An antipsychotic agent used in SCHIZOPHRENIA.
National Institutes of Health

Papers overview

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2012
2012
OBJECTIVE The present study evaluated inhaled loxapine for the acute treatment of agitation in patients with bipolar I disorder… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND There is a need for a rapid-acting, non-injection, acute treatment for agitation. AIMS To evaluate inhaled loxapine… (More)
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2011
2011
Medicinal aerosol products (metered dose and dry powder inhalers) require characterization testing over a wide range of use and… (More)
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2011
2011
OBJECTIVE The objective of this study was to assess the efficacy and safety of inhaled loxapine in the treatment of agitation in… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Public health advisories have warned that the use of atypical antipsychotic medications increases the risk of death… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Cortical inhibition (CI) deficits have been proposed as a pathophysiologic mechanism in schizophrenia. This study… (More)
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1996
1996
The purpose of this trial was to assess the potential utility of adjunctive treatment with a typical neuroleptic for patients… (More)
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1996
1996
Positron emission tomography (PET) studies of typical neuroleptics suggest that 60% to 80% of striatal D2 occupancy may be… (More)
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Highly Cited
1994
Highly Cited
1994
Clozapine and haloperidol produce different induction patterns of c-fos expression in the forebrain, with haloperidol increasing… (More)
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Highly Cited
1975
Highly Cited
1975
The present study has compared the abilities of clozapine, haloperidol, chlorpromazine and loxapine to induce dopamine (DA… (More)
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