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Low-Density Lipoproteins
Known as:
low density lipoprotein (LDL)
, Low density lipoprotein
, beta-Lipoproteins
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A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller…
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National Institutes of Health
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Related topics
Related topics
28 relations
Acanthocytosis
Cholesterol
Hypercholesterolemia
In Blood
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Broader (2)
Blood lipoproteins
Lipoproteins
Narrower (10)
LDL-1
LDL-2
acetoacetyl-LDL
acetyl-LDL
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1996
Highly Cited
1996
Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor
S. Acton
,
A. Rigotti
,
K. Landschulz
,
Shangzhe Xu
,
H. Hobbs
,
M. Krieger
Science
1996
Corpus ID: 249922
High density lipoprotein (HDL) and low density lipoprotein (LDL) are cholesterol transport particles whose plasma concentrations…
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Highly Cited
1993
Highly Cited
1993
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.
S. Ishibashi
,
Michael S. Brown
,
J. Goldstein
,
R. Gerard
,
R. Hammer
,
J. Herz
Journal of Clinical Investigation
1993
Corpus ID: 24474748
We employed homologous recombination in embryonic stem cells to produce mice lacking functional LDL receptor genes. Homozygous…
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Review
1993
Review
1993
Role of oxidised low density lipoprotein in atherogenesis.
J. Witztum
British heart journal
1993
Corpus ID: 5717081
Overview of the concept ofoxidative modification ofLDL There can be no doubt now that there is a continuum of increasing risk for…
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Review
1991
Review
1991
Role of oxidized low density lipoprotein in atherogenesis.
J. Witztum
,
D. Steinberg
Journal of Clinical Investigation
1991
Corpus ID: 46101303
Evidence to support an important role of oxidative modification in mediating the atherogenicity of LDL continues to grow. New…
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Highly Cited
1989
Highly Cited
1989
Low density lipoprotein undergoes oxidative modification in vivo.
W. Palinski
,
M. Rosenfeld
,
+7 authors
J. Witztum
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 25036629
It has been proposed that low density lipoprotein (LDL) must undergo oxidative modification before it can give rise to foam cells…
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Highly Cited
1988
Highly Cited
1988
Low-density lipoprotein subclass patterns and risk of myocardial infarction.
M. Austin
,
J. Breslow
,
C. Hennekens
,
Julie E. Buring
,
W. Willett
,
R. Krauss
Journal of the American Medical Association (JAMA…
1988
Corpus ID: 2071833
The association of low-density lipoprotein (LDL) subclass patterns with coronary heart disease was investigated in a case-control…
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Highly Cited
1984
Highly Cited
1984
Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.
U. Steinbrecher
,
S. Parthasarathy
,
D. Leake
,
J. Witztum
,
D. Steinberg
Proceedings of the National Academy of Sciences…
1984
Corpus ID: 25614600
Low density lipoprotein (LDL) incubated with cultured endothelial cells from rabbit aorta or human umbilical vein is altered in…
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Highly Cited
1979
Highly Cited
1979
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition.
J. Goldstein
,
Y. K. Ho
,
S. Basu
,
Michael S. Brown
Proceedings of the National Academy of Sciences…
1979
Corpus ID: 21503180
Resident mouse peritoneal macrophages were shown to take up and degrade acetylated (125)I-labeled low density lipoprotein ((125)I…
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Highly Cited
1977
Highly Cited
1977
Cholesterol determination in high-density lipoproteins separated by three different methods.
M. Lopes-Virella
,
P. Stone
,
S. Ellis
,
John A. Coiweil
Clinical Chemistry
1977
Corpus ID: 17823979
We describe a simplified method for measuring high-density lipoprotein cholesterol in serum after very-low- and low-density…
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Highly Cited
1977
Highly Cited
1977
High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study.
T. Gordon
,
W. Castelli
,
M. Hjortland
,
W. Kannel
,
T. Dawber
American Journal of Medicine
1977
Corpus ID: 33721343
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