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Low Density Lipoprotein Receptor-Related Protein-5

Known as: Low Density Lipoprotein Receptor-Related Protein-5 [Chemical/Ingredient], LRP-5, Lipoprotein Receptor Related Protein 5 
LDL-receptor related protein that combines with FRIZZLED RECEPTORS at the cell surface to form receptors that bind WNT PROTEINS. The protein plays an… Expand
National Institutes of Health

Papers overview

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2011
2011
AIMS Atherosclerosis plaque development includes infiltration of inflammatory cells, accumulation of lipids and fibrous cap… Expand
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2010
2010
OBJECTIVE Mutations in the low-density lipoprotein receptor-related protein 5 gene (LRP5) underlie osteoporosis-pseudoglioma… Expand
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Review
2009
Review
2009
The Wnt family of secreted ligands act through many receptors to stimulate distinct intracellular signalling pathways in… Expand
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES The goal of this research was to define the cellular mechanisms involved in myxomatous mitral valve disease and… Expand
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Highly Cited
2004
Highly Cited
2004
Stature, bone size, and bone mass are interrelated traits with high heritability, but the major genes that govern these… Expand
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Highly Cited
2003
Highly Cited
2003
A Wnt coreceptor low-density lipoprotein receptor-related protein 5 (LRP5) plays an essential role in bone accrual and eye… Expand
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Highly Cited
2002
Highly Cited
2002
Osteoporosis is a complex disease that affects >10 million people in the United States and results in 1.5 million fractures… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Osteoporosis is a major public health problem of largely unknown cause. Loss-of-function mutations in the gene for low… Expand
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Highly Cited
2001
Highly Cited
2001
To understand how the Wnt coreceptor LRP-5 is involved in transducing the canonical Wnt signals, we identified Axin as a protein… Expand
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Highly Cited
2001
Highly Cited
2001
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, encoding the low-density… Expand
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