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Lorazepam

Known as: O-Chlorooxazepam, 7-Chloro-5-(2-chlorophenyl)-1, 3-Dihydro-3-Hydroxy-1,4- Benzodiazepin-2-one, O-Chloroxazepam 
A benzodiazepine with anxiolytic, anti-anxiety, anticonvulsant, anti-emetic and sedative properties. Lorazepam enhances the effect of the inhibitory… 
National Institutes of Health

Related topics

Related topics

45 relations

Broader (9)

Anti-Anxiety AgentsAnticonvulsantsAntiemeticsBenzodiazepine
Anxiety DisordersCatatoniaDepressive disorderEpilepsies, Partial

Narrower (14)

Apo-LorazepamAtivanD-12524Idalprem

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Effect of age and cardiopulmonary bypass on the pharmacokinetics of lorazepam.
The pharmacokinetics of lorazepam after 0.03 mg/kg intravenous administration was investigated in 14 surgical patients (nasal… 
1985
1985
Interaction of propoxyphene with diazepam, alprazolam and lorazepam.
Healthy volunteers received single doses of three benzodiazepines (diazepam, 10 mg i.v.; alprazolam, 1.0 mg orally; lorazepam, 2… 
1985
1985
A comparison of the effects of lorazepam with those of propranolol on experimentally-induced anxiety and performance.
In a double-blind cross-over study the effects of propranolol (80 mg) and of lorazepam (1 or 2.5 mg) were assessed in normal… 
1985
1985
Propranolol interactions with diazepam, lorazepam, and alprazolam.
Healthy subjects received single doses of diazepam (5 to 10 mg iv), lorazepam (2 mg iv), or alprazolam (1 mg orally) on two… 
Highly Cited
1983
Highly Cited
1983
Catecholamine and cortisol responses to sufentanil-O2 and alfentanil-O2 anaesthesia during coronary artery surgery
The effects of alfentanil-O2 and sufentanil-O2 anaesthesia on plasma catecholamines and cortisol were investigated in 32 patients… 
1982
1982
The effect of intravenous cimetidine on the absorption of orally administered diazepam and lorazepam.
1 The effect of intravenous cimetidine 200 mg or 400 mg on the absorption of lorazepam 2.5 mg tablet and diazepam 10 mg tablet… 
Highly Cited
1978
Highly Cited
1978
Analysis of lorazepam and its glucuronide metabolite by electron-capture gas--liquid chromatography. Use in pharmacokinetic studies of lorazepam.
This paper describes a rapid and sensitive method for analysis of lorazepam and its glucuronide metabolite in plasma and urine… 
1978
1978
Pharmacology of lorazepam.
Lorazepam reduced conflict behavior in rats and monkeys, inhibited pentylenetetrazol- and electroshock-induced convulsions… 
1978
1978
Comparative metabolism of lorazepam in man and four animal species.
: The metabolic disposition of lorazepam (Wy-4036) in man, dog, cat, rat and miniature swine is compared. Except in the cat… 
1971
1971
Wy 4036 (lorazepam): a study of its use in premedication.
In 150 otherwise healthy gynaecological patients the sedative properties of a new benzodiazepine, lorazepam, have been studied…