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Loperamide Hydrochloride
Known as:
Hydrochloride, Loperamide
, loperamide hcl
, Loperamide Monohydrochloride
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The hydrochloride salt form of loperamide, a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity. Loperamide acts on the…
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National Institutes of Health
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Related topics
Related topics
15 relations
Colonic Diseases, Functional
Constipation
Diarrhea
Drug Allergy
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Narrower (1)
Imodium
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Behavior of printable formulations of loperamide and caffeine on different substrates--effect of print density in inkjet printing.
N. Genina
,
Dan H. R. Fors
,
Mirja Palo
,
J. Peltonen
,
N. Sandler
International journal of pharmaceutics
2013
Corpus ID: 23263989
Highly Cited
2010
Highly Cited
2010
P-Glycoprotein Function at the Blood–Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide
W. Kreisl
,
J. Liow
,
+6 authors
R. Innis
Journal of Nuclear Medicine
2010
Corpus ID: 13785747
Permeability-glycoprotein (P-gp), an efflux transporter in several organs, acts at the blood–brain barrier to protect the brain…
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Highly Cited
2009
Highly Cited
2009
P-Glycoprotein Function at the Blood–Brain Barrier Imaged Using 11C-N-Desmethyl-Loperamide in Monkeys
J. Liow
,
W. Kreisl
,
+7 authors
R. Innis
Journal of Nuclear Medicine
2009
Corpus ID: 13783732
11C-Loperamide is an avid substrate for P-glycoprotein (P-gp), but it is rapidly metabolized to 11C-N-desmethyl-loperamide (11C…
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Highly Cited
2008
Highly Cited
2008
Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.
N. Lazarova
,
S. Zoghbi
,
+7 authors
V. Pike
Journal of Medicinal Chemistry
2008
Corpus ID: 13791687
[(11)C]Loperamide has been proposed for imaging P-glycoprotein (P-gp) function with positron emission tomography (PET), but its…
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Highly Cited
2008
Highly Cited
2008
Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury
Y. Guan
,
L. Johanek
,
+5 authors
S. Raja
Pain
2008
Corpus ID: 38929994
Highly Cited
2007
Highly Cited
2007
Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone.
H. Dupont
,
Zhi-Dong Jiang
,
+10 authors
Francisco Martinez Sandoval
Clinical Gastroenterology and Hepatology
2007
Corpus ID: 22278512
Review
1998
Review
1998
Fortnightly review : Faecal incontinence
M. Kamm
1998
Corpus ID: 72888486
Abstract Faecal incontinence affects men and women of all ages. Daily or weekly episodes occur in about 2% of the adult…
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Highly Cited
1992
Highly Cited
1992
Anal sphincter-saving operations for chronic ulcerative colitis.
K. Kelly
American Journal of Surgery
1992
Corpus ID: 6198513
Highly Cited
1990
Highly Cited
1990
Treatment of traveler's diarrhea with sulfamethoxazole and trimethoprim and loperamide.
C. Ericsson
,
H. Dupont
,
J. Mathewson
,
M. West
,
P. Johnson
,
J. A. Bitsura
JAMA
1990
Corpus ID: 32975966
In a randomized, double-blind, placebo-controlled trial, 227 US adults with acute diarrhea in Mexico received a single dose of…
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Highly Cited
1986
Highly Cited
1986
Comparison of loperamide with bismuth subsalicylate for the treatment of acute travelers' diarrhea.
P. Johnson
,
C. Ericsson
,
H. Dupont
,
D. Morgan
,
J. A. Bitsura
,
L. Wood
JAMA
1986
Corpus ID: 33699408
Loperamide hydrochloride was compared with bismuth subsalicylate for the treatment of acute nondysenteric travelers' diarrhea in…
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