Skip to search formSkip to main contentSkip to account menu

Loperamide Hydrochloride

Known as: Hydrochloride, Loperamide, loperamide hcl, Loperamide Monohydrochloride 
The hydrochloride salt form of loperamide, a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity. Loperamide acts on the… 
National Institutes of Health

Related topics

Related topics

15 relations
Colonic Diseases, FunctionalConstipationDiarrheaDrug Allergy

Narrower (1)

Imodium

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Behavior of printable formulations of loperamide and caffeine on different substrates--effect of print density in inkjet printing.
Highly Cited
2010
Highly Cited
2010
P-Glycoprotein Function at the Blood–Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide
Permeability-glycoprotein (P-gp), an efflux transporter in several organs, acts at the blood–brain barrier to protect the brain… 
Highly Cited
2009
Highly Cited
2009
P-Glycoprotein Function at the Blood–Brain Barrier Imaged Using 11C-N-Desmethyl-Loperamide in Monkeys
11C-Loperamide is an avid substrate for P-glycoprotein (P-gp), but it is rapidly metabolized to 11C-N-desmethyl-loperamide (11C… 
Highly Cited
2008
Highly Cited
2008
Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.
[(11)C]Loperamide has been proposed for imaging P-glycoprotein (P-gp) function with positron emission tomography (PET), but its… 
Highly Cited
2008
Highly Cited
2008
Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury
Highly Cited
2007
Highly Cited
2007
Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone.
Review
1998
Review
1998
Fortnightly review : Faecal incontinence
Abstract Faecal incontinence affects men and women of all ages. Daily or weekly episodes occur in about 2% of the adult… 
Highly Cited
1992
Highly Cited
1992
Anal sphincter-saving operations for chronic ulcerative colitis.
  • K. Kelly
  • American Journal of Surgery
  • 1992
  • Corpus ID: 6198513
Highly Cited
1990
Highly Cited
1990
Treatment of traveler's diarrhea with sulfamethoxazole and trimethoprim and loperamide.
In a randomized, double-blind, placebo-controlled trial, 227 US adults with acute diarrhea in Mexico received a single dose of… 
Highly Cited
1986
Highly Cited
1986
Comparison of loperamide with bismuth subsalicylate for the treatment of acute travelers' diarrhea.
Loperamide hydrochloride was compared with bismuth subsalicylate for the treatment of acute nondysenteric travelers' diarrhea in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)