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Loperamide Hydrochloride

Known as: Hydrochloride, Loperamide, loperamide hcl, Loperamide Monohydrochloride 
The hydrochloride salt form of loperamide, a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity. Loperamide acts on the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The primary goal of the current work was to study the applicability of precision inkjet printing in fabrication of personalized… Expand
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Highly Cited
2010
Highly Cited
2010
Permeability-glycoprotein (P-gp), an efflux transporter in several organs, acts at the blood–brain barrier to protect the brain… Expand
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Highly Cited
2009
Highly Cited
2009
11C-Loperamide is an avid substrate for P-glycoprotein (P-gp), but it is rapidly metabolized to 11C-N-desmethyl-loperamide (11C… Expand
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Highly Cited
2008
Highly Cited
2008
[(11)C]Loperamide has been proposed for imaging P-glycoprotein (P-gp) function with positron emission tomography (PET), but its… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS Antimotility agents provide rapid temporary relief of acute diarrhea, whereas antibiotics slowly cure the… Expand
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Highly Cited
2004
Highly Cited
2004
We hypothesised that the depletion of propylene glycol from topical formulations applied at clinically relevant doses… Expand
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Highly Cited
1990
Highly Cited
1990
In a randomized, double-blind, placebo-controlled trial, 227 US adults with acute diarrhea in Mexico received a single dose of… Expand
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Highly Cited
1986
Highly Cited
1986
Loperamide hydrochloride was compared with bismuth subsalicylate for the treatment of acute nondysenteric travelers' diarrhea in… Expand
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Highly Cited
1982
Highly Cited
1982
Loperamide hydrochloride (4 mg t.d.s.) was compared with codeine phosphate (60 mg t.d.s.) in a double blind crossover study of… Expand
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1979
1979
A pharmacokinetic study of the antidiarrheal agent loperamide hydrochloride (Imodium) was conducted in six male subjects. The… Expand
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