Loperamide Hydrochloride

Known as: Hydrochloride, Loperamide, loperamide hcl, Loperamide Monohydrochloride 
The hydrochloride salt form of loperamide, a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity. Loperamide acts on the… (More)
National Institutes of Health

Papers overview

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2013
2013
Peripherally acting opioids are potentially attractive drugs for the clinical management of certain chronic pain states due to… (More)
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2009
2009
UNLABELLED P-glycoprotein (P-gp) is a membrane-bound efflux pump that limits the distribution of drugs to several organs of the… (More)
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2008
2008
UNLABELLED 11C-Loperamide is an avid substrate for P-glycoprotein (P-gp), but it is rapidly metabolized to 11C-N-desmethyl… (More)
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2008
2008
[(11)C]Loperamide has been proposed for imaging P-glycoprotein (P-gp) function with positron emission tomography (PET), but its… (More)
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2007
2007
BACKGROUND & AIMS Antimotility agents provide rapid temporary relief of acute diarrhea, whereas antibiotics slowly cure the… (More)
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2004
2004
The purpose of the present study was to develop a standard protocol for loperamide hydrochloride bioequivalence testing. For this… (More)
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1990
1990
In a randomized, double-blind, placebo-controlled trial, 227 US adults with acute diarrhea in Mexico received a single dose of… (More)
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1982
1982
Loperamide hydrochloride (4 mg t.d.s.) was compared with codeine phosphate (60 mg t.d.s.) in a double blind crossover study of… (More)
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1979
1979
A pharmacokinetic study of the antidiarrheal agent loperamide hydrochloride (Imodium) was conducted in six male subjects. The… (More)
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