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Long-acting Granulocyte Colony-stimulating Factor Analog SPI-2012

Known as: LAPS-GCSF, SPI-2012 
A long-acting, recombinant analog of the endogenous human granulocyte colony-stimulating factor (G-CSF) with hematopoietic activity. Similar to G-CSF… 
National Institutes of Health

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Related topics

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Cytokine Receptor ActivationHematopoietic stem cellsPositive Regulation of Cell DifferentiationReceptor Activation Process

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HM10460A

Papers overview

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2017
2017
Abstract 1347:In vivoefficacy of eflapegrastim in rats with chemotherapy-induced neutropenia
Introduction: Eflapegrastim (SPI-2012, HM10460A) is a novel, long-acting recombinant human granulocyte colony-stimulating factor… 
2016
2016
Abstract OT3-02-13: Randomized phase 3 study of a novel, long-acting G-CSF (SPI-2012) versus pegfilgrastim in the management of chemotherapy-induced neutropenia in early-stage breast cancer patients…
Background: SPI-2012 is a distinct biologic that uses the innovative, proprietary long-acting protein/peptide discovery… 
2016
2016
Abstract P1-10-05: Randomized phase 2, open-label, dose-ranging study of a novel, long-acting G-CSF (SPI-2012) or pegfilgrastim for the management of neutropenia in patients with breast cancer (BC…
Background: SPI-2012 is a distinct biologic that uses the innovative proprietary long-acting protein/peptide discovery technology… 
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