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Lofepramine

Known as: Lofepramine [Chemical/Ingredient], Lopramine, Ethanone, 1-(4-chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)- 
A psychotropic IMIPRAMINE derivative that acts as a tricyclic antidepressant and possesses few anticholinergic properties. It is metabolized to… 
National Institutes of Health

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13 relations

Narrower (5)

FeprapaxGamanilLeo 640Lofepramine Hydrochloride
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Tricyclic Antidepressive Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Actions of lofepramine, a new tricyclic antidepressant, and desipramine on electrophysiological and mechanical parameters of guinea pig atrial and papillary muscles.
The effects of lofepramine on the isolated guinea pig atrial trabeculae were compared with those of desipramine. The preparations… 
Review
1986
Review
1986
Clinical Features and Management of Self-Poisoning with Newer Antidepressants
SummaryOver the last decade a number of antidepressants have been introduced which differ either chemically, pharmacologically or… 
1985
1985
Cardiovascular effects of single doses of the antidepressants amitriptyline and lofepramine in healthy subjects.
In a placebo-controlled double blind study, single oral doses of lofepramine (140 mg and 210 mg) and amitriptyline (100 mg and… 
1982
1982
Haloperidol plasma/red blood cell ratios and clinical efficacy.
1979
1979
Prediction of Lofepramine-Response in Depression Based on Response to Partial Sleep Deprivation
Wirz-Justice Wirz-Justice v. Zerssen 
1979
1979
A double-blind trial with amitriptyline and lofepramine in the treatment of endogenous depression.
A double-blind trial was undertaken to compare the antidepressant efficacy and the side effects of Lofepramine with those of… 
1976
1976
[Behavioral pharmacology of a new antidepressant, lopramine].
The behavioral effects of lopramine [N-methyl-N-(4-chlorobenzoyl-methyl)-3-(10, 11-dihydro-5H-dibenz (b,f) azepin-5-yl… 
1976
1976
[Electroencephalographic effects of lopramine].
Electroencephalographic (EEG) effects of lopramine, a new antidepressant, were investigated in rabbits with chronic electrode… 
1976
1976
[Double-blind comparative study on the effects of lofepramine and amitriptyline in depressive outpatients (author's transl)].
The anticholinergic side-effects of tricyclic antidepressants are unpleasant for the patients. Lofepramine, a new tricyclic… 
1975
1975
[Clinical trial of lofepramine versus imipramine].
Lofepramin is a new derivative of imipramine. Its effects and side effects were compared to those of imipramine in a double-blind… 
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