Liver X Receptors

Known as: Liver X Receptor, Oxysterol Receptors, Nuclear, Nuclear Oxysterol Receptors 
Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
The liver X receptors (LXRs) are pivotal regulators of lipid homeostasis in mammals. These transcription factors control the… (More)
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Review
2006
Review
2006
The liver X receptors (LXRs) are nuclear receptors that play central roles in the transcriptional control of lipid metabolism… (More)
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Highly Cited
2003
Highly Cited
2003
Macrophages have important roles in both lipid metabolism and inflammation and are central to the pathogenesis of atherosclerosis… (More)
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Review
2003
Review
2003
The liver X receptors alpha and beta (LXRalpha and LXRbeta) are members of the nuclear receptor family of proteins that are… (More)
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Highly Cited
2002
Highly Cited
2002
The nuclear receptors LXRalpha and LXRbeta have been implicated in the control of lipogenesis and cholesterol homeostasis. Ligand… (More)
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Highly Cited
2002
Highly Cited
2002
Mutations in the ATP-binding cassette (ABC) transporters ABCG5 and ABCG8 have recently been shown to cause the autosomal… (More)
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Highly Cited
2002
Highly Cited
2002
Recent studies have identified the liver X receptors (LXR alpha and LXR beta) as important regulators of cholesterol metabolism… (More)
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Highly Cited
2000
Highly Cited
2000
Tangier disease, a condition characterized by low levels of high density lipoprotein and cholesterol accumulation in macrophages… (More)
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Highly Cited
1999
Highly Cited
1999
LXRalpha and -beta are nuclear receptors that regulate the metabolism of several important lipids, including cholesterol and bile… (More)
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Highly Cited
1997
Highly Cited
1997
Members of the peroxisome proliferator-activated receptor (PPAR) family might be involved in pathologies with altered lipid… (More)
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