Liver X Receptor-Like Family

Known as: NR1H, LXR, LXR Family 
A nuclear receptor family that binds oxysterols or bile acids and, after forming a heterodimer with a member of the retinoid X receptor (RXR) family… (More)
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
Liver X receptors (LXRs) are nuclear hormone receptors that regulate cholesterol and fatty acid metabolism in liver tissue and in… (More)
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Review
2004
Review
2004
The nuclear receptors liver X receptor (LXR)alpha and LXRbeta are sensors of cholesterol metabolism and lipid biosynthesis. They… (More)
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Highly Cited
2003
Highly Cited
2003
The control of lipid and glucose metabolism is closely linked. The nuclear receptors liver X receptor (LXR)alpha and LXR beta… (More)
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Highly Cited
2002
Highly Cited
2002
Mutations in the ATP-binding cassette (ABC) transporters ABCG5 and ABCG8 have recently been shown to cause the autosomal… (More)
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Highly Cited
2001
Highly Cited
2001
The nuclear receptors liver X receptor alpha (LXRalpha) (NR1H3) and LXRbeta (NR1H2) are important regulators of genes involved in… (More)
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Highly Cited
2001
Highly Cited
2001
Previous work has implicated the nuclear receptors liver X receptor alpha (LXR alpha) and LXR beta in the regulation of… (More)
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Highly Cited
2001
Highly Cited
2001
In an attempt to identify transcription factors which activate sterol-regulatory element-binding protein 1c (SREBP-1c… (More)
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Highly Cited
2000
Highly Cited
2000
Tangier disease, a condition characterized by low levels of high density lipoprotein and cholesterol accumulation in macrophages… (More)
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Highly Cited
2000
Highly Cited
2000
The liver X receptors (LXRs) are members of the nuclear hormone receptor superfamily that are bound and activated by oxysterols… (More)
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Highly Cited
1999
Highly Cited
1999
The major metabolic pathway for elimination of cholesterol is via conversion to bile acids. In addition to this metabolic… (More)
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