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Liver X Receptor-Like Family

Known as: NR1H, LXR, LXR Family 
A nuclear receptor family that binds oxysterols or bile acids and, after forming a heterodimer with a member of the retinoid X receptor (RXR) family… 
National Institutes of Health

Related topics

Related topics

19 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression
Liver X receptors (LXRs) contribute not only to maintain cholesterol homeostasis but also to control cell growth. However, the… 
2011
2011
A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expression
2010
2010
Liver X receptor agonist treatment reduced splanchnic ischemia and reperfusion injury
LXR is another member of the superfamily of nuclear hormone receptors that heterodimerizes with RXR and regulates the… 
2008
2008
Effect of niacin on LXRalpha and PPARgamma expression and HDL-induced cholesterol efflux in adipocytes of hypercholesterolemic rabbits.
BACKGROUND Adipose tissue contains a large amount of cholesterol and performs a buffer function for circulating cholesterol… 
2007
2007
Adipocyte fatty acid-binding protein (aP2), a newly identified LXR target gene, is induced by LXR agonists in human THP-1 cells
The liver X receptors (LXRα and LXRβ), ligand-activated transcription factors, belong to the superfamily of nuclear hormone… 
2007
2007
Heterotic and genetic components in 4x4 diallel mating experiment for egg production traits in chickens
Two local breeds, namely Fayoumi (F) and Dandarawi (D) and two exotic ones named Rhode Island Red (R) and White Leghorn (L) were… 
2006
2006
Oxidized low density lipoprotein suppresses lipopolysaccharide-induced inflammatory responses in microglia: oxidative stress acts through control of inflammation.
2004
2004
Effects of Pravastatin on the Expression of ATP-Binding Cassette Transporter A1
In vitro inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase causes the suppression of liver X receptor (LXR… 
2004
2004
Oxidized LDL upregulated ATP binding cassette transporter-1 in THP-1 macrophages.
AIM To study the effect of oxidized low density lipoprotein (ox-LDL) on ATP binding cassette transporter A1 (ABCA1) in THP-1… 
2000
2000
Genomic structure and mapping of human orphan receptor LXR alpha: upregulation of LXRa mRNA during monocyte to macrophage differentiation.
In order to identify changes in the gene expression profile during human monocyte/macrophage differentiation in the presence of… 
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