Lipoxal
National Institutes of Health
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SummaryResults of clinical trials with oxaliplatin in treating glioblastoma are dismal. Previous works showed that intravenous (i…
Introduction: To date, a growing number of advanced anticancer nanomedicines (e.g., Doxil®, Lipoxal®, DepoCyte®) have entered…
AIM
To determine the benefits of irradiation at the time of maximum linking of oxaliplatin to the DNA of tumor cells, and…
AbstractTreatment of glioblastoma with platinum compounds modestly improves progression-free survival and may cause toxic effects…
BACKGROUND
We choose to test the effect of associating chemo-radiotherapy at 8 h (the highest level of DNA-platinum) and 48 h…
SummaryLiposomal formulations of cisplatin and oxaliplatin (Lipoplatin™ and Lipoxal™, respectively) were recently proposed to…
Lipoplatin, currently under phase III evaluation, is a novel liposomal cisplatin formulation highly effective against cancers…
BACKGROUND
Lipoxal is a liposomal oxaliplatin, which reduces the cytotoxic agent's adverse reactions without reducing…