Lipotecan
National Institutes of Health
Papers overview
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BACKGROUND
The discovery of effective therapeutic options for treating metastatic poorly differentiated neuroendocrine carcinoma…
Introduction: TLC388 (Lipotecan) is a potent Topoisomerase-1 inhibitor and it can disrupt both Sonic Hedgehog and HIF1-α pathways…
e13618 Background: The phase I first-in-human study of TLC388 (Lipotecan) examined the MTD, safety, anti-tumor activity and…