Levetiracetam

Known as: (S)-alpha-Ethyl-2-oxo-1-pyrrolidineacetamide, 1-Pyrrolidineacetamide, Alpha-ethyl-2-oxo-,(S)-, etiracetam, S-isomer 
A pyrrolidine with antiepileptic activity. The exact mechanism through which levetiracetam exerts its effects is unknown but does not involve… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
In light of the rising prevalence of Alzheimer's disease (AD), new strategies to prevent, halt, and reverse this condition are… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE We report the results of a prospective study of the efficacy and tolerability of levetiracetam, a new antiepileptic… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE To assess the efficacy and tolerability of adjunctive levetiracetam in patients with uncontrolled generalized tonic… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To evaluate the efficacy and tolerability of levetiracetam (LEV) as adjunctive therapy in children (4 to 16 years) with… (More)
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Highly Cited
2004
Highly Cited
2004
Here, we show that the synaptic vesicle protein SV2A is the brain binding site of levetiracetam (LEV), a new antiepileptic drug… (More)
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Highly Cited
2003
Highly Cited
2003
The prevalence and psychopathologic features of psychiatric adverse events (PAE) in 517 patients taking levetiracetam (LEV) were… (More)
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Review
2000
Review
2000
Levetiracetam is a novel orally active antiepileptic drug with a unique preclinical profile. It has a high therapeutic index and… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE To evaluate the efficacy and safety of 500 mg bid and 1500 mg bid levetiracetam as adjunctive therapy for refractory… (More)
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Highly Cited
1998
Highly Cited
1998
The protective and adverse effect potentials of levetiracetam ((S)-alpha-ethyl-2-oxo-pyrrolidine acetamide) in rodent models of… (More)
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Highly Cited
1998
Highly Cited
1998
We have previously shown that the novel anticonvulsant levetiracetam exerts potent anticonvulsant activity against both focal and… (More)
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