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Leucine-Specific tRNA

Known as: RNA, Transfer, Leu, tRNA(Leu), RNA, Leu Transfer 
A transfer RNA which is specific for carrying leucine to sites on the ribosomes in preparation for protein synthesis.
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

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pre-tRNA(Leu)

Papers overview

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Highly Cited
2017
Highly Cited
2017
ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications
Abstract ALKBH1 is a 2-oxoglutarate- and Fe2+-dependent dioxygenase responsible for multiple cellular functions. Here, we show… 
Highly Cited
2011
Highly Cited
2011
Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production
An important function of the β-amino acid, taurine, is the regulation of oxidative stress. However, taurine is neither a… 
Highly Cited
2006
Highly Cited
2006
Identification of human tRNA:m5C methyltransferase catalysing intron-dependent m5C formation in the first position of the anticodon of the pre-tRNA(CAA)Leu
We identified a human orthologue of tRNA:m5C methyltransferase from Saccharomyces cerevisiae, which has been previously shown to… 
Highly Cited
2005
Highly Cited
2005
The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer–editing conformation
Leucyl-tRNA synthetase (LeuRS) has a specific post-transfer editing activity directed against mischarged isoleucine and similar… 
Highly Cited
2004
Highly Cited
2004
A genetically encoded photocaged amino acid.
We have developed a second orthogonal tRNA/synthetase pair for use in yeast based on the Escherichia coli tRNALeu/leucyl tRNA… 
Highly Cited
2001
Highly Cited
2001
Maternally Inherited Diabetes and Deafness: A Multicenter Study
Mitochondrial (mt) gene abnormalities cause disease due to defects in oxidative production of energy (1). In 1990, Goto and… 
Highly Cited
1996
Highly Cited
1996
Gene rearrangements in snake mitochondrial genomes: highly concerted evolution of control-region-like sequences duplicated and inserted into a tRNA gene cluster.
Mitochondrial DNA (mtDNA) regions corresponding to two major tRNA gene clusters were amplified and sequenced for the Japanese pit… 
Highly Cited
1990
Highly Cited
1990
A point mutation in the mitochondrial tRNA(Leu)(UUR) gene in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes).
Highly Cited
1990
Highly Cited
1990
An ancient group I intron shared by eubacteria and chloroplasts
Introns have been found in the genomes of all major groups of organisms except eubacteria. The presence of introns in… 
Highly Cited
1981
Highly Cited
1981
Two conserved sequence blocks within eukaryotic tRNA genes are major promoter elements
The split promoter sequences of a tRNALeuCUG gene of Xenopus laevis have been mapped to nucleotides 13–20 and 51–64 of the… 
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