Large granular lymphocyte

Known as: Large Granular Lymphocytes, granular large lymphocytes, LGL 
A population of large-sized lymphocytes found in human peripheral blood with slightly eccentric nuclei and abundant cytoplasmic azurophilic granules… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2017
05019742017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Chronic lymphoproliferative disorders of natural killer cells (CLPD-NKs) and T-cell large granular lymphocytic leukemias (T-LGLs… (More)
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Highly Cited
2008
Highly Cited
2008
T cell large granular lymphocyte (T-LGL) leukemia features a clonal expansion of antigen-primed, competent, cytotoxic T… (More)
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Highly Cited
2004
Highly Cited
2004
Aggressive natural killer-cell leukemia (ANKL) is a rare form of large granular lymphocyte leukemia, which is characterized by a… (More)
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Highly Cited
2001
Highly Cited
2001
Large granular lymphocyte (LGL) leukemia is characterized by the expansion of antigen-activated cytotoxic T lymphocytes. These… (More)
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2000
2000
Morbidity and mortality in patients with T large granular lymphocyte (T-LGL) leukemia resutt from infections acquired during… (More)
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1998
1998
CD95 (Fas)-induced apoptosis plays a critical role in the elimination of activated lymphocytes and induction of peripheral… (More)
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Highly Cited
1996
Highly Cited
1996
The Fas ligand (FasL), a member of the tumor necrosis factor family, induces apoptosis in Fas–bearing cells. The membrane–bound… (More)
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Highly Cited
1995
Highly Cited
1995
Large granular lymphocyte (LGL) 1 is a cell surface glycoprotein expressed on a subset (50%) of C57BL/6 natural killer (NK) cells… (More)
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Highly Cited
1984
Highly Cited
1984
Purified cytoplasmic granules from cytotoxic rat large granular lymphocytes (LGL) tumors were cytolytic to erythrocytes… (More)
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Highly Cited
1981
Highly Cited
1981
Recent evidence, has demonstrated an association between a subpopulation of peripheral blood mononuclear cells, morphologically… (More)
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