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Large T-Antigen

Known as: Antigen, Large T, Large T Antigen, T Antigen, Large 
National Institutes of Health

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Broader (1)

Viral Tumor Antigens

Papers overview

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2016
2016
Modulation of innate immune signaling by the small T antigen of Merkel cell polyomavirus, the causative agent of Merkel cell skin cancer
Merkel cell Polyomavirus (MCPyV) is implicated in the pathogenesis of Merkel cell carcinoma (MCC), a rare and highly aggressive… 
2015
2015
Participation of the viral oncoproteins E 6 and E 7 in dysregulation of the mechanisms of cellular proliferation and death
The E6 and E7 oncoproteins are the main driving force in the transforming potential of the human papillomavirus (HPV) in cervical… 
2013
2013
An anti-large T-antigen strategy to develop anti-JCV drugs
There are currently no JCV-specific therapies available for clinical use. This study evaluates viral large T antigen (LTA) as a… 
2011
2011
[Sequencing and analysis of the complete genome sequence of WU polyomavirus in Fuzhou, China].
WU polyomavirus (WUPyV), a new member of the genus Polyomavirus in the family Polyomaviridae, is recently found in patients with… 
2010
2010
A Modified Yeast One-hybrid Sytem to Investigate Protein-protein and Protein: DNA Interactions
A modified yeast one-hybrid (MY1H) system has been developed for in vivo investigation of simultaneous protein-protein and… 
2005
2005
Negative Regulation of the Neu Promoter by the SV 4 O Large T Antigen 1
The neu gene is amplified and its protein product is overexpressed in certain human tumors. The adenovirus 5 El a gene product…