Large T-Antigen

Known as: Antigen, Large T, Large T Antigen, T Antigen, Large 
 
National Institutes of Health

Papers overview

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2013
2013
Clonal integration of Merkel cell polyomavirus (MCV) DNA into the host genome has been observed in at least 80% of Merkel cell… (More)
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2010
2010
We demonstrated previously that expression of simian virus 40 (SV40) large T antigen (LT), without a viral origin, is sufficient… (More)
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2010
2010
Merkel cell polyomavirus (MCPyV) is detected in approximately 80% of Merkel cell carcinomas (MCC). Yet, clonal integration and… (More)
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Highly Cited
2009
Highly Cited
2009
Simian virus 40 (SV40) large T antigen (LT) is a multifunctional protein that is important for viral replication and oncogenic… (More)
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2009
2009
Dear Editor, MCPyV, a new human oncogenic polyoma virus, appears etiologic for the classic, rare, aggressive Merkel Cell… (More)
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2006
2006
Large T antigen (LTag) from simian virus 40 (SV40) is an ATP-driven DNA helicase that specifically recognizes the core of the… (More)
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2003
2003
Tumor spindle cells in all clinical types of Kaposi's sarcoma (KS) are infected with Kaposi's sarcoma-associated herpesvirus… (More)
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2002
Highly Cited
2002
While it is clear that cancer arises from the accumulation of genetic mutations that endow the malignant cell with the properties… (More)
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2000
2000
The ability of polyomavirus large T antigen (LT) to promote cell cycling, to immortalize primary cells, and to block… (More)
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2000
2000
The simian double strand DNA tumor virus SV40 encodes the 90-kDa multi-functional protein, large T antigen (LT). LT functions by… (More)
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