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Lanoconazole

Known as: (4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-1-imidazolylacetonitrile, alpha-[(E)-4-(o-Chlorophenyl)-1,3-dithiolan-2-ylidene]imidazole-1-acetonitrile, latoconazole 
National Institutes of Health

Papers overview

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2017
2017
Imidazoles are well known heterocyclic compounds having important feature of a variety of medicinal agents. Studies with… 
2009
2009
以1-咪唑基乙腈碳和氢氧化钾反应得到二钾盐,再与2-(1,2-二氯乙基)氯苯环合反应得到目标化合物拉诺康唑,总收率为34.0%.关键中间体2-(1,2-二氯乙基)氯苯以邻氯苯乙烯为原料,经氯气加成得到.并研究了拉诺康唑异构体的转化. 
2006
2006
国内で流行しているTrichophyton tonsurans 感染症起因菌の薬剤感受性を調べることを目的として, 感染症患者より採取した臨床分離株10株を用いて各種抗真菌薬のin vitro… 
2006
2006
Aim To synthesize lanoconazole and the key interme diate 1-(2-chlorophenyl)-1, 2-ethanediol dimethanesulfonate in a simple way… 
2000
2000
Imidazole antifungal agents have been successfully developed in medicine mainly for the treatment of superficial cutaneous fungal…